Results 191 to 200 of about 27,799 (249)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

The mythological and archaeological perspectives on penectomy and orchiectomy: The case of Cybele and Attis. [PDF]

Andrology
Kaya C.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

<i>Toxoplasma gondii</i> infection in domestic cats and northern fur seals of the Pribilof Islands, Alaska. [PDF]

Int J Parasitol Parasites Wildl
Dawant T, Gerhold R, Scott D, Su C, Divine L, Williams M, Ream R, Gelatt T, Duncan C.   +8 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Beliefs about god buffer against the health risks of loneliness and social isolation in five major religions and 22 countries. [PDF]

Sci Rep
Wormley AS, Vornlocher C, Baldwin CR, Rodriguez M.   +3 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Faith in the Midst of Trials: Understanding Depression and Christian Coping Strategies Among Cancer Patients in Eastern Europe. [PDF]

Cureus
Jugrin D, Jitaru AA, Brinza C, Burlacu A.   +3 more
europepmc   +1 more source

Factors associated with adolescent use of tobacco products in the Upper East Region of Ghana: A cross-sectional study. [PDF]

Tob Induc Dis
Logo DD, Kodali PB, Anaman-Torgbor J, Chaffee BW, Ling PM, Bialous S, Owusu-Dabo E.   +6 more
europepmc   +1 more source