Results 71 to 80 of about 29,415 (268)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

From the Ultimate God to the Virtual God: Post-Ontotheological Perspectives on the Divine in Heidegger, Badiou, and Meillassoux [PDF]

open access: yesMeta: Research in Hermeneutics, Phenomenology and Practical Philosophy, 2014
The Heideggerian account of the ontotheological constitution of Western metaphysics has been extremely influential for contemporary philosophy of religion and for philosophical perspectives on theology and the divine.
Jussi Backman
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Survey of audience reception in the Sistine Chapel: decoding the message of sacred art

open access: yesChurch, Communication and Culture, 2018
The Sistine Chapel in the Vatican is home to the most famous frescoes in the world that also have a profound religious significance and unique history. This case study analyses a survey of audience reception (2017) in the Sistine Chapel.
Emanuela Edwards
doaj   +1 more source

The Divine Processions and the Divine Energies

open access: yesPhilosophy of Religion: Analytic Researches, 2020
The concept of the divine energies (energeiai) is commonly associated with the late Byzantine theologian Gregory Palamas. In fact, however, it has biblical origins and figures prominently in Greek patristic theology from at least the fourth century. Here I briefly trace its history beginning with the Pauline usage of energeia and continuing through the
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Divine authority as divine parenthood

open access: yesReligious Studies
Abstract In this article, I argue that God is authoritative over us because he is our divine, causal parent. As our causal parent, God has duties to relate to us, but he can only fulfil those duties if he has the practical authority to give us commands aimed at our sanctification.
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Mixed Methods for Study of Gender Issues in Access, Application, and Attitudes Toward ICT in Higher Education Institutions in Papua New Guinea

open access: yesSAGE Open, 2015
For more than a century, there has been an ongoing paradigm debate between qualitative and quantitative methodological communities that has led to a growing interest in the mixed methods approach.
Iwona Kolodziejczyk
doaj   +1 more source

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