Results 121 to 130 of about 1,397 (281)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins   +9 more
wiley   +1 more source

To Obey is to Worship: A Reply to Brown and Nagasawa

open access: yesAnkara Üniversitesi İlahiyat Fakültesi Dergisi
In their paper titled “I Can’t Make You Worship Me”, Campbell Brown and Yujin Nagasawa (2005) argue that divine command theory is incompatible with the view that we have a moral obligation to worship God. In this paper I examine their concern and suggest
Hayyan Sheikh
doaj  

Twin Crystal Moiré Metasurfaces for Crossing Flat‐Band Transport

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces twin crystal moiré metasurfaces, breaking in‐plane symmetry to enable reconfigurable acoustic wave manipulation. By adjusting the twin angle and interlayer twist angle, various combinations of hyperbolic, flat bands, and elliptic states can be synthesized in the system.
Shida Fan   +9 more
wiley   +1 more source

Ethics and God: the Divine Command Theory and the Euthyphro Dilemma [PDF]

open access: yes
Some people claim that ethics depends on God: unless there’s a God who makes actions right and wrong, no actions would be objectively right or wrong, good or bad.
Nobis, Nathan
core  

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng   +16 more
wiley   +1 more source

The Semiotics of Syntax: Integrating X-Bar and Dependency Grammar in a Saussurean Framework

open access: yesJurnal Al Bayan: Jurnal Jurusan Pendidikan Bahasa Arab
The Arabic language of the Qur'an exhibits a distinctive nominal sentence structure that is rich in theological and rhetorical meaning. This article presents how nominal constructions in Surah al-Maʿārij reflect theological messages and rhetorical ...
Chaterina Puteri Doni   +4 more
doaj   +1 more source

Incorporating divine command theory in the world of accountants’ professional codes of conduct based on Abrahamic religions [PDF]

open access: yes, 2016
Humanizing humans should be the substantial goal for all scholars in the varied disciplines of social science. Living in a value-free society is becoming a big challenge for the survival of both individuals and societies, in all aspects of humans ...
Khalil, Ala’a Mustafa Deeb
core  

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

open access: yesAdvanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones   +14 more
wiley   +1 more source

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