Results 81 to 90 of about 57,185 (292)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Repetition, difference and liturgical participation in Coleridge's 'The ancient mariner' [PDF]

open access: yes, 2007
Theological interpretations of ‘The Rime of the Ancient Mariner’ have sometimes been judged to do little more than to compound the problem of interpretation.
Larkin, Peter
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Towards an Interpretation of the Ch. 13 from Georges Moschambar’s Antirrhetics against Veccus within the Context of the Byzantine Doctrine of the 13th–15th Centuries on the Interpenetration of the Persons of the Holy Trinity [PDF]

open access: yesВестник Екатеринбургской духовной семинарии
The author analyzes two crucial ideas from Chapter 13 of the Antirrhetics against the Doctrines and Writings of Veccus, penned in 1281 by the Byzantine anti-Latin polemicist Georges Moschambar, a prominent representative of the proto-Palamite tradition ...
Dmitry I. Makarov
doaj   +1 more source

Are You There, God? It’s Me, the Theist: On the Viability and Virtue of Non-Doxastic Prayer [PDF]

open access: yes, 2022
In this article, I explore the possibility of what I call “non-doxastic theistic prayer”, namely prayer that proceeds without full belief in God – or in the kind of God who could be the recipient of such prayer.
Griffioen, Amber
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Medieval Water Energies: Philosophical, Hydro-Social, and Intellectual

open access: yesOpen Library of Humanities, 2018
This essay argues for the consideration of energy and an energy-based humanities model in the study of water in the Middle Ages. It also proposes that ‘energy’, when discussed in the context of the Middle Ages, is in fact a study of ‘energies’, derived ...
James L. Smith
doaj   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

The Double Vision: Language and Meaning in Religion [PDF]

open access: yes, 1993
Reviewed Book: Frye, Northrop. The Double Vision: Language and Meaning in Religion.
Froese, H. Victor
core   +1 more source

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