Results 111 to 120 of about 201,281 (315)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

The Necessity and Goodness of Animals in Sijistānī’s Kashf Al-Maḥjūb

open access: yesPhilosophies
The Neoplatonic notion of “emanation” implies a required progression through hierarchical stages, originating from the highest principle (the One or God) and cascading down through a series of principles.
Peter Adamson, Hanif Amin Beidokhti
doaj   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

PRESENCE AND ABSENCE: GOODNESS AND EVIL IN PARADISE LOST (MILTON)

open access: yes, 1985
This dissertation explores and defines the nature and generation of goodness and evil in Paradise Lost. Chapter 1 first demonstrates the inability of the Satanist debate to answer its central question: if all creation is originally good, what then is the
KILBORN, JUDITH MARGARET
core  

The nature of God's goodness

open access: yes
Contemporary expositions of God’s goodness err either (1) by subjecting God to moral norms, which is to question His sovereignty and aseity, or (2) by failing to establish that God will always act in accordance with moral norms, which removes the theist ...
Sivyer, Philip
core   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song   +10 more
wiley   +1 more source

Assaying J. L. Mackie\\\'s View on Evil Based on Suhrewardi\\\'s Philosophy

open access: yesComparative Theology, 2014
J. L. Mackie is among those philosophers who have highlighted evil as evidence to God's nonexistence. Suhrewardi's ideas of evil can partially answer some of his critiques.
S.Moreza Hosseini Shahroudi   +1 more
doaj  

Aurelius Augustine in the Orthodox Tradition – Basic Topoi of Distinction

open access: yesForum Theologicum Sardicense
What is the attitude toward Aurelius Augustine in the Eastern Church after the schism of 1054 and in contemporary times? Although he is regarded as one of the respected Fathers of the Church and known as the “Teacher of the West,” Augustine is not ...
Dimitrina Cherneva
doaj   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

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