Results 91 to 100 of about 234,582 (307)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
‘I Am That I Am’ and divine titles: A Reformed theological critique
Verbum et EcclesiaThe heavenly title ‘I Am That I Am’ (Ex 3:14) signifies God’s self-existence and transcendence, which are essential to biblical theology and Christ’s ‘I am’ declarations in the Gospel of John.
Ndidzulafhi Mudau
doaj +1 more source
THE NAME OF GOD AND ORTHODOX ICONS WITHIN THE CONTEXT OF PATRISTICTHEOLOGY [PDF]
Вестник Православного Свято-Тихоновского гуманитарного университета: Серия I. Богословие, философия, 2007 his article deals with an aspect of modern polemics against onomatodoxy. The paperanalyses the statement of onomatodoxy supporters that if an Orthodox icon is sanctified by theinscription of the corresponding name, then, this name turns out to be Divine ...
P. I. MALKOV
doaj
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Comparative Theology, 2014 The most important aspect of divine names and attributes is their semantics. Human beings’ interpretation of this aspect will have a profound impact on the type of relationship they have with God as it is by these names and attributes that we know ...
ٍReza Berenjkar, Abouzar Nourouzi
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Written with the Finger of God: Divine and Human Writing in Exodus
, 2014 The presence of writing in the book of Exodus must be considered not only for its contribution to the narrative as story, but also as a witness to several key socio-political issues (such as the interplay of textuality and orality in ancient Israel), for
Doak, Brian R.
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source