Results 121 to 130 of about 234,582 (307)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Délibérer avec les dieux : attributs onomastiques et prise de décision à Athènes aux époques classique et hellénistique

open access: yesPallas
Sources on the role ascribed to divine figures in the decision-making process are scarce, even in Athens during the Classical and Hellenistic periods. However, an analysis of the names of the deities summoned during the various stages of the collective ...
Julie Bernini, Sylvain Lebreton
doaj   +1 more source

Actual Grace and the Elevation of the Secular [PDF]

open access: yes, 2015
This paper develops and integrates several strands of thought represented in recent contributions that the author has tried to make to the secularization-sacralization debate.1 That debate is both ecclesial and theological, and the two contexts are ...
Doran, Robert M.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Dionisio Aeropagita, filosofía neoplatónica y revelación cristiana. Nota sobre tres publicaciones recientes acerca del Corpus dionysiacum

open access: yesPatristica et Mediaevalia, 2010
Aquí se propone una lectura sinóptica de tres obras recientes que tienen en común la acentuación de aspectos filosóficos y teológicos del pensamiento areopagítico: Christian Schafer estudia la filosofía del CD en The Philosophy of Dionysius the ...
Julio César Lastra Sheridan
doaj  

Shape and origin of Bhaktivedanta Swami's image of christianity : an essay [PDF]

open access: yes, 1998
0. Introduction and theses. 1. Bhaktivedanta Swami's view of Christianity. 1.1. The Bible; 1.2. Jesus; 1.3. History of the church. 2. Bhaktivedanta Swami's religious socialization. 2.1. Childhood; 2.2 College; 2.3. Vaishnava-teachers. 3.
Schmidt, Peter
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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