Results 231 to 240 of about 233,762 (309)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

The effect of mindfulness-based stress reduction on self-compassion and parent-child relationship quality in health caregivers. [PDF]

BMC Psychol
Rakhshani T, Bagherfard A, Kamyab A, Jeihooni AK.   +3 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Cultural influences on road safety in Vanuatu: masculinity norms and their impact on dangerous driving behaviors. [PDF]

Front Public Health
Fanai S, Okyere E, Marfoh K.
europepmc   +1 more source

The Theological Virtues and Participation in Active and Passive Spiration [PDF]

, 2014
Doran, Robert M.
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Acute kidney injury in non-renal medical and surgical admissions in a secondary hospital in Cameroon: recognition and outcomes. [PDF]

Pan Afr Med J
Teuwafeu DG, Ayonghe A, Mbua RG, Nkoke C, Mahamat M, Divine M, Ashuntantang G.   +6 more
europepmc   +1 more source

Overshadowed by Enoch\u27s Greatness: Two Tablets Traditions from the Book of Giants to Palaea Historica [PDF]

, 2001
Orlov, Andrei
core   +1 more source

The potential and challenges of an online Bible study group for persons with disabilities. [PDF]

Afr J Disabil
Opperman T, Botha M.
europepmc   +1 more source

Ecocentrism vs. Anthropocentrism: To the Core of the Dilemma to Overcome It. [PDF]

Linacre Q
Frantz P, Rego F, Barbas S.
europepmc   +1 more source