Results 61 to 70 of about 2,517,735 (227)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

ELEMENTOS SOBRE LA HISTORIA DEL CONCEPTO DE DESARROLLO SEGÚN LOS ECONOMISTAS THEOTONIO DOS SANTOS Y GILBERT RIST

open access: yesTendencias, 2013
El artículo tiene como propósito presentar la percepción y las inquietudes que dos importantes pensadores económicos ofrecen a través de sus obras sobre dependencia económica y desarrollo, como punto de partida en la reflexión que se ha iniciado sobre ...
Francisco Javier Criollo   +5 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Memoria Anual del Departamento de Aguas Subterráneas - 1969

open access: yes, 1969
Fil: Dirección Nacional de Geología y Minería.
Argentina. Dirección Nacional de Geología y Minería. División Hidrogeología
core   +1 more source

Diagnóstico de la diarrea aguda

open access: yesARS Medica, 2017
Sin ...
M. Cortesía, P. Vial, J. Nataro
doaj   +1 more source

Auditoría externa del ICONTEC

open access: yes, 2018
Visita del ICONTEC a la Universidad de Medellín con miras la renovación de la certificación en calidad que se realizó del 22 al 25 de mayo de 2018. Foto 1. Mesa principal visita del Icontec: de izquierda a derecha se encuentra la auditora líder, Claudia
División de Planeación
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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