Results 41 to 50 of about 125,463 (212)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A pertinência da categoria divisão sexual do trabalho para a análise da morfologia do trabalho na contemporaneidade (The relevance of category sexual division of labor to the analysis of work in...) Doi: 10.5212/Emancipacao.v.15i1.0003

open access: yesEmancipação, 2016
Resumo: O presente artigo tem por objetivo refletir sobre a morfologia do trabalho na contemporaneidade, onde analisaremos a categoria divisão sexual do trabalho,conceituando e debatendo sua pertinência para compreender a organização e o processo do ...
Renata Gomes da Costa   +1 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Androcentrismo y teoría económica, ¿qué tienen que decir las mujeres al respecto?

open access: yesCuadernos de Economía Crítica, 2015
En el artículo se presentan algunas de las críticas provenientes de la economía feminista al paradigma neoclásico en la ciencia económica. Se presenta de qué forma las teorías neoclásicas reproducen un sesgo androcéntrico en sus conceptos de mercado ...
Natalia Flores Garrido
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Les lieux de la répression au prisme du genre : la rue parisienne au croisement des pratiques émeutières et des pratiques policières (XVIIIe siècle)

open access: yesGenre & Histoire, 2016
What spatial logics are at stake during the repression of Parisian popular uprisings in the XVIIIth century? The analysis of urban space during this period allows one to grasp the relationship between popular social practices and the police apparatus ...
Clara Chevalier
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

PfPPM2 signalling regulates asexual division and sexual conversion of human malaria parasite Plasmodium falciparum

open access: yesNature Communications
Malaria parasite undergoes interesting developmental transition in human and mosquito host. While it divides asynchronously in the erythrocytes, it switches to sexual forms, which is critical for disease transmission. We report a novel signalling pathway
Akanksha Rawat   +9 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy