Results 131 to 140 of about 6,584,437 (368)

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

General Divisibility Criteria [PDF]

open access: yesarXiv, 2014
We believe we have made progress in the age-old problem of divisibility rules for integers. Universal divisibility rule is introduced for any divisor in any base number system. The divisibility criterion is written down explicitly as a linear form in the digits of the test number.
arxiv  

Containment and Division

open access: yesPRISM, 2018
PRISM: Casting New Light on Learning, Theory and Practice, Vol 2 No 1 (2018): Education, Pedagogy and Social Class (Winter)
openaire   +5 more sources

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

open access: yesMolecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen   +6 more
wiley   +1 more source

Division Rings with Ranks [PDF]

open access: yesarXiv, 2016
Any superrosy division ring (i.e. a division ring equipped with an abstract notion of rank) is shown to be centrally finite. Furthermore, division rings satisfying a generalized chain condition on definable subgroups are studied. In particular, a division ring of burden n has dimension at most n over its center, and any definable group of definable ...
arxiv  

The Inverse Relation Between the Size and the Number of Parts

open access: yesJETEN, 2016
This study analyzes children’s understanding of the inverse relationship between size and number of parts when fractions and division situations are involved. A survey by questionnaire was conducted with 42 Portuguese fourth-graders trying to address two
Ema Mamede, Isabel Vasconcelos
doaj  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Clinical significance of stratifying prostate cancer patients through specific circulating genes

open access: yesMolecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian   +12 more
wiley   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

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