Results 51 to 60 of about 290,510 (307)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

General Divisibility Algorithms

Journal of Sensor Networks and Data Communications
In my paper, a divisibility rule named the Queen function is de- scribed, which has been generalized for every integer and encompasses all pre- viously established divisibility rules. Subsequently, the paper discusses other areas where this function is instrumental. These include simplifying ratios, generating prime numbers, and more.
openaire   +2 more sources

SRT Division Algorithms as Dynamical Systems

SIAM Journal on Computing, 2004
Summary: Sweeney-Robertson-Tocher (SRT) division, as it was discovered in the late 1950s, represented an important improvement in the speed of division algorithms for computers at the time. A variant of SRT division is still commonly implemented in computers today.
McCann, Mark, Pippenger, Nicholas
openaire   +3 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Intelligent Partition Strategy of Distributed Photovoltaic Cluster in Distribution Network Based on SLM-RBF

Shanghai Jiaotong Daxue xuebao
Access of large-scale distributed power supply to the distribution network brings dimensionality disaster to the optimal dispatching of the distribution network.
BU Qiangsheng, LÜ Pengpeng, LI Weiqi, LUO Fei, YU Jingwen, DOU Xiaobo, HU Qinran
doaj   +1 more source

Implementasi Algoritma Genetika untuk Penjadwalan Instruktur Training ICT UIN Sunan Kalijaga

JISKA (Jurnal Informatika Sunan Kalijaga), 2017
ICT training instructor scheduling involves components such as the division of the day, sessions, classroom, and availability time of instructor which is different every day.
Niki Min Hidayati Robbi, Nurochman Nurochman   +1 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Convex optimization–based multi-user detection in underwater acoustic sensor networks

International Journal of Distributed Sensor Networks, 2018
Multi-carrier code-division multiple access is an important technical means for high-performance underwater acoustic sensor networks. Nevertheless, severe multiple access interference is a huge challenge.
Jianping Wang, Shujing Zhang, Wei Chen, Dechuan Kong, Zhou Yu   +4 more
doaj   +1 more source