Results 121 to 130 of about 125,618 (262)
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
The Impact of Unilateral Divorce on Crime [PDF]
In this paper, we evaluate the impact of unilateral divorce on crime. First, using crime rates from the FBI’s Uniform Crime Report program for the period 1965-1998 and differences in the timing in the introduction of the reform, we find that unilateral ...
Giolito, Eugenio P. +1 more
core +2 more sources
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
The impact of divorce laws on marriage-specific capital [PDF]
This paper considers how divorce law alters the incentives for couples to invest in their marriage, focusing on the impact of unilateral divorce laws on investments in new marriages.
Betsey Stevenson
core
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
The topography of the divorce plateau [PDF]
The probability of divorce in the U.S. has remained constant for the last two decades at about 'half of all marriages.' While this estimate is well established, and marked differentials in divorced rates are well known, there are no reliable estimates of
Larry L. Bumpass, R. Kelly Raley
core
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Socioeconomic differentials in divorce risk by duration of marriage [PDF]
Using register-based data on Finnish first marriages that were intact at the end of 1990 (about 2.1 million marriage-years) and followed up for divorce in 1991-1993 (n = 21,204), this research explored the possibility that the effect of spouses ...
Marika Jalovaara
core
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Does cancer affect the divorce rate? [PDF]
Discrete-time hazard regression models were employed to register and census data on 1.4 million Norwegian married couples from 1974-2001 to explore the probability of divorce following cancer illness.
Astri Syse, Øystein Kravdal
core