Results 71 to 80 of about 61,518 (280)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Gray Divorce in the Shadow of Modernization: Changing Family Dynamics in Türkiye

open access: yesSocial Sciences
Gray divorce, defined as the dissolution of marriages among individuals aged 50 and above, has become an increasingly significant issue in Türkiye. Official statistics in Türkiye show that between 2001 and 2024, divorces among individuals aged 50 and ...
Selcuk Aydin   +2 more
doaj   +1 more source

Marriage, divorce and economic growth

open access: yesAnnales Etyka w Życiu Gospodarczym, 2019
The aim of the study is to estimate the impact of the so-called family social capital (family ties capital) on economic growth. We hypothesise that marital dissolution expresses decrease in the capacity for cooperation, collaboration and sharing ...
Paweł Baranowski, Jan Jacek Sztaudynger
doaj   +1 more source

Outliving Love: Marital Estrangement in an African Insurance Market [PDF]

open access: yes, 2016
Marital estrangement and formal divorce are vital conjunctures for married women’s kinship relations and life course, where a horizon of future possibilities are revalued and negotiated at the interstices of custom, law, and social and ritual obligations.
Golomski, Casey
core   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Parenting after Divorces: A Qualitative Research

open access: yesTaḥqīqāt-i ̒Ulūm-i Raftārī, 2017
Aim and Background: Parenting is one of the hardest tasks of parents and a determining factor in children’s psychological health. One of the factors influencing parenting is divorce.
رضا خجسته مهر   +3 more
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

A JURIDICAL EXAMINATION OF MARRIAGE DISPENSATION AND DIVORCE IN RELIGIOUS COURT; INSIGHTS FROM SADD AL-DZARI’AH

open access: yesJurnal Al-Dustur
Unraveling the intricate dynamics of marriage dispensations and divorces, this study dives deep into the Sidenreng Rappang Religious Court which is located at South Sulawesi, through the lens of sadd al-dzari’ah.
Hannat Waladat Maryam   +4 more
doaj   +1 more source

Socio-Economic And Divorce in Aceh Province

open access: yesMimbar, 2019
Socio-economic factors are always the benchmark of domestic life. There is an assumption that a household disharmony is caused by economic issues referred to as the highest number of divorce cases registered at Mahkamah Shari’a (Shari’s Court) of Aceh ...
Afzal Sabri, Abd Jamal, Muhammad Nasir
doaj   +1 more source

Divorce laws and divorce rate in the US [PDF]

open access: yesThe B.E. Journal of Macroeconomics, 2011
At the end of the 1960s, the U.S. divorce law underwent major changes and the divorce rate almost doubled in all of the states. This paper shows that changes in property division, alimony transfers, and child custody assignments account for a substantial share of the increase in the divorce rate, especially for young, college educated couples with ...
openaire   +9 more sources

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