Results 151 to 160 of about 162,823 (266)

Challenges of Pain in Parkinson's Disease: Results from the OCEAN Study

open access: yesMovement Disorders, EarlyView.
Abstract Background Pain is a common non‐motor symptom in Parkinson’s disease (PD) and is often associated to fluctuations. Objective The OpiCapone Effect on motor fluctuations and pAiN (OCEAN) study evaluated the effect of opicapone on fluctuation‐related pain when added to levodopa therapy in PD patients.
Kallol Ray Chaudhuri   +13 more
wiley   +1 more source

A Phase 1 Study of Convection‐Enhanced Delivery of Intraputaminal AAV2‐GDNF in Advanced Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder. Neurotrophic therapeutic approaches have been limited in part by incomplete delivery to the putamen. We developed image‐guided convection‐enhanced delivery with real‐time monitoring to improve intraputaminal distribution of neurotrophic gene therapy. Objectives To
John D. Heiss   +10 more
wiley   +1 more source

Real‐World Evaluation of Bilateral Magnetic Resonance–Guided Focused Ultrasound Thalamotomy in Essential Tremor

open access: yesMovement Disorders, EarlyView.
Abstract Background Magnetic resonance–guided focused ultrasound (MRgFUS) thalamotomy is effective in treating essential tremor (ET) with an adequate safety profile. Objective The aim of the study was to evaluate the real‐world safety and efficacy of staged bilateral MRgFUS thalamotomy in ET and its impact on patient's quality of life (QoL) and patient‐
Dolores Vilas   +8 more
wiley   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

A Cross-Sectional Survey of Cannabis Use and Utility Among Patients Experiencing Dizziness. [PDF]

open access: yesBrain Sci
Elmi P   +7 more
europepmc   +1 more source

Sustainable Metal Recovery From E‐Waste: Exploring Greener Leachates in Hydrometallurgical Processes

open access: yesMetalMat, EarlyView.
Recycling of electronic waste to synthesize valuable metals using green leachate. ABSTRACT The accumulation of electronic waste (e‐waste) poses environmental hazards and leads to the loss of valuable metals such as gold, silver, copper, and rare earth elements.
Shassatha Paul Saikat   +4 more
wiley   +1 more source

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