Results 201 to 210 of about 336,939 (388)

Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez   +8 more
wiley   +1 more source

Vestibular influence on cranio-cervical pain:A case report [PDF]

open access: yes, 2012
Cross, Caroline   +2 more
core  

Effects of a two‐night hospitalization program as a specific health guidance on obesity and cardiovascular disease risk factors

open access: yesJournal of General and Family Medicine, EarlyView.
Abstract Background To assess the effects of a two‐night hospitalization program conducted at our hospital as part of a domestic health guidance system. This program is designed for lifestyle modification within a health checkup framework for metabolic syndrome. Methods This is a single‐center, retrospective observational study. We reviewed the medical
Maki Okazaki   +5 more
wiley   +1 more source

Critical mistakes in managing chronic constipation in the older person and how to avoid them: A narrative review

open access: yesJournal of General and Family Medicine, EarlyView.
Abstract Objectives This narrative review identifies pitfalls in managing constipation in older adults and provides evidence‐based recommendations to avoid them. Methods A selective literature search was conducted across electronic databases (PubMed, MEDLINE, Embase, and Cochrane Library) to identify relevant publications on constipation management in ...
Madunil Niriella   +3 more
wiley   +1 more source

Wernicke encephalopathy observed in a cancer patient receiving terminal‐stage home care

open access: yesJournal of General and Family Medicine, EarlyView.
Abstract We report an 80 year old man in the terminal stage of cancer receiving home care. On the 18th day after starting home care, he experienced a sudden onset of impaired consciousness, unsteadiness of gait, and ophthalmoplegia. Based on the clinical symptoms and a prolonged loss of appetite, Wernicke encephalopathy (WE) was suspected. Thiamine 100 
Minoru Saiki   +4 more
wiley   +1 more source

Is manual therapy effective for cervical dizziness? A systematic review and meta-analysis of randomized controlled trials. [PDF]

open access: yesBMC Musculoskelet Disord
Carrasco-Uribarren A   +6 more
europepmc   +1 more source

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