Results 221 to 230 of about 345,532 (386)

In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug Transporters

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug candidate for the treatment of chronic hepatitis C virus infection. Potential drug–drug interactions (DDIs) of bemnifosbuvir as a substrate or perpetrator with regard to ATP‐binding cassette (ABC) and solute carrier (SLC) transporters were evaluated in vitro and in clinical studies ...
Xiao‐Jian Zhou   +9 more
wiley   +1 more source

Exogenous Melatonin and Sleep Quality: A Scoping Review of Systematic Reviews

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Melatonin is increasingly used to treat sleep disturbances, yet its overall efficacy remains unclear due to variability in existing evidence. This scoping review aimed to synthesize systematic reviews with meta‐analyses assessing the effects of exogenously administered melatonin on sleep quality in humans.
Samyuktha Iyer   +3 more
wiley   +1 more source

DIZZiness treatment through implementation and clinical strategy Tactics-2 (DIZZTINCT-2) project-a clinical trial protocol. [PDF]

open access: yesTrials
Meurer WJ   +14 more
europepmc   +1 more source

Wernicke encephalopathy observed in a cancer patient receiving terminal‐stage home care

open access: yesJournal of General and Family Medicine, EarlyView.
Abstract We report an 80 year old man in the terminal stage of cancer receiving home care. On the 18th day after starting home care, he experienced a sudden onset of impaired consciousness, unsteadiness of gait, and ophthalmoplegia. Based on the clinical symptoms and a prolonged loss of appetite, Wernicke encephalopathy (WE) was suspected. Thiamine 100 
Minoru Saiki   +4 more
wiley   +1 more source

Deep White Matter Lesions on MRI, and Not Silent Brain Infarcts Are Related to Headache and Dizziness of Non-specific Cause in Non-Stroke Japanese Subjects.

open access: bronze, 2000
Masatoshi Fujishima   +14 more
openalex   +2 more sources

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