Results 301 to 310 of about 345,532 (386)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Anti‐Neuroinflammatory and Anti‐Inflammatory Effects of the NLRP3 Inhibitor NT‐0796 in Subjects with Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Inhibition of Nod‐like receptor protein 3 (NLRP3) inflammasome within the central nervous system (CNS) is a promising therapeutic target for the treatment of Parkinson's disease (PD). Objectives This phase 1b open‐label study was conducted in elderly healthy volunteers (HV) and PD patients.
Nicholas Clarke, Peter Thornton, Valérie Reader, Nicola Lindsay, Zsofia Digby, Bianca Mullen, Michelle Gorman, Eric Jacobson, Grant Langdon, Hilary Johnstone, Alistair Wheeler, Alan P. Watt   +11 more
wiley   +1 more source

Can Dizziness Be Related to Insomnia Severity and Sleep Quality in Young Adults? [PDF]

Turk Arch Otorhinolaryngol
Konukseven Ö, Saçlı Y, Küçük Ceyhan A.   +2 more
europepmc   +1 more source

Dizziness and Headaches in a College Quarterback

, 2004
Richard Okragly
openalex   +1 more source

Relationship between post-COVID-19 symptoms and daily physical activity. [PDF]

Front Rehabil Sci
Sarmento A, Webber S, Sargent S, Tittlemier B, Sanchez-Ramirez DC.   +4 more
europepmc   +1 more source

RRP12 Variants Are Associated With Autosomal Recessive Brain Calcifications

Movement Disorders, EarlyView.
Abstract Background Primary brain calcifications are observed in several inherited diseases due to different pathogenic mechanisms, including the disruption of the neurovascular unit, mitochondrial dysfunction, and impaired nucleic acid metabolism.
Edoardo Monfrini, Paola Rinchetti, Mathieu Anheim, Anna Klingseisen, Ouhaid Lagha‐Boukbiza, Zhidong Cen, Dehao Yang, Xinhui Chen, Reza Maroofian, Henry Houlden, Gioia Cappelletti, Anne‐Claire Richard, Olivier Quenez, Camilo Toro, Steven J. Frucht, Francesco Lotti, Wei Luo, David Hunt, Gael Nicolas, Giulietta M. Riboldi   +19 more
wiley   +1 more source

Post-COVID-19 dizziness associated with a patulous eustachian tube. [PDF]

BMJ Case Rep
den Dunnen J, Bauwens A, Versfeld NJ, Goderie T.   +3 more
europepmc   +1 more source

A Network Centered on the Visual‐Motor Cortex Is Critically Involved in Postural Abnormality in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Postural abnormality (PA) is a key motor symptom in Parkinson's disease (PD) that leads to disability and death. However, the pathophysiology underlying PA is still unknown. Objective The objective of this study was to explore the neural patterns behind PAs and measures toward functional restoration using repetitive transcranial ...
Zhuang Wu, Sha Zhu, Ronghua Hong, Zhuoyu Zhang, Yanzi Peng, Jingxing Zhang, Lizhen Pan, Qiang Guan, Yuhui Chen, Lingjing Jin   +9 more
wiley   +1 more source

Two Vertebral Arteries Running Above the Articular Pillars of the Cervical Vertebrae: A Case Report. [PDF]

Orthop Res Rev
Li S, Zhang H, Yang G, Tang M, Gao Q.
europepmc   +1 more source