Results 51 to 60 of about 4,028 (197)

Glyoxalase‐1 Inhibition Leads to Ferroptosis Induction in Lung Cancer Cells: A Dual Mechanism of Action of Hydroxamic Acids Derived from Cysteine

ChemMedChem, Volume 21, Issue 1, January 2026.
A set of three cysteine‐derived hydroxamic acids were synthesized and evaluated for human gloxalase‐1 inhibition and ferroptosis induction activities. Among them, compound 2 exhibited a potent inhibitory effect against human glyoxalase‐1 and induced ferroptosis in non‐small cell lung cancer cell lines, increasing reactive oxygen species production and ...
Josué Martínez‐Miranda, Dolores Aguilar‐Cázares, Angélica Flores–Flores, Miguel Ángel Santos‐Contreras, José S. López‐González, Rodrigo Aguayo‐Ortiz, Rogélio Hernández‐Pando, Francisco Hernández‐Luis   +7 more
wiley   +1 more source

Discrepancy Between the Ability of Wine Experts and Consumers in Identifying Grape Smoke Exposure in Different Wine Matrices in California

Journal of Food Science, Volume 90, Issue 10, October 2025.
ABSTRACT Volatile phenols (VPs) are present in fresh smoke from wildfires due to thermal degradation of wood lignin and can absorb into grape berry skins where they are rapidly glycosylated. VPs and their glycosides can impact the sensory profile of wines that are characterized by smoky, medicinal aromas and a retro‐nasal ashy “aftertaste.” Anecdotal ...
Lik Xian Lim, Cristina Medina‐Plaza, Ignacio Arias‐Perez, Yan Wen, Bishnu Neupane, Larry Lerno, Jean‐Xavier Guinard, Anita Oberholster   +7 more
wiley   +1 more source

OBTENTION OF RABIES ANTIGEN THROUGH BHK21 CELLS ADHERED TO MICROCARRIERS

Revista do Instituto de Medicina Tropical de São Paulo, 1998
Four rabies antigen batches were produced from virus suspensions resulting from BHK21 cells adhered to microcarriers (Cytodex 1), inoculated and cultured in a bioreactor. In parallel the methodology of production of rabies virus through cultures of BHK21
Neuza M. FRAZATTI GALLINA, Rosana de LIMA PAOLI, Izilda A. FRANCISCO, Gislaine de CASTRO GARCIA, Regina M. MOURÃO FUCHES   +4 more
doaj   +1 more source

Study of linear energy transfer effect on rib fracture in breast cancer patients receiving pencil‐beam‐scanning proton therapy

Medical Physics, Volume 52, Issue 5, Page 3428-3438, May 2025.
Abstract Background In breast cancer patients treated with pencil‐beam scanning proton therapy (PBS), the increased linear energy transfer (LET) near the end of the proton range can affect nearby ribs. This may associate with a higher risk of rib fractures.
Yunze Yang, Kimberly R. Gergelis, Jiajian Shen, Arslan Afzal, Trey C. Mullikin, Robert W. Gao, Khaled Aziz, Dean A. Shumway, Kimberly S. Corbin, Wei Liu, Robert W. Mutter   +10 more
wiley   +1 more source

Efecto biocida del «barbasco» Lonchocarpus utilis (Smith,1930) como regulador de larvas de mosquitos

Revista Peruana de Biología, 2013
Se realizaron 7 bioensayos de laboratorio para evaluar la capacidad biocida de Lonchocarpus utilis (Smith,1930) «barbasco» sobre 7000 larvas de tercer y cuarto estadio de Anopheles benarrochi (Gabaldón, 1941), vector primario de malaria, en Yurimaguas y ...
Carlos Mariños, Julia Castro, Diana Nongrados   +2 more
doaj   +1 more source

Tailored Functionalization of Plasmonic AgNPs/C:H:N:O Nanocomposite for Sensitive and Selective Detection

Journal of Biophotonics, Volume 18, Issue 2, February 2025.
AgNPs/C:H:N:O nanocomposite as a highly selective and sensitive transducer for detecting Borrelia bacteria was developed. The functionalized surface enables precise immobilization of spirochetes, with a measurable LSPR red‐shift indicating pathogen presence.
Sanjay Kumar, Hana Maskova, Anna Kuzminova, Paval Curda, Lenka Doudova, Jan Sterba, Ondřej Kylián, Ryan O. M. Rego, Vítězslav Straňák   +8 more
wiley   +1 more source

Acute Toxicity Assessment, In Vitro Antacid and Cytoprotective Effects of Root Bark Aqueous Extract of Diospyros mespiliformis on Water Immersion Stress‐Induced Gastric Ulcers in Rats

Canadian Journal of Gastroenterology and Hepatology, Volume 2025, Issue 1, 2025.
Objective: The objective of the present study was to evaluate the antacid and cytoprotective effects of root bark aqueous extract of Diospyros mespiliformis (RBAEDM). Materials and Methods: Thirty rats were grouped into six groups of five rats each, namely, three control groups (normal, negative and positive) and three test groups.
Vandza Luc Vandi, André Perfusion Amang, Christophe Mezui, Gael Tchokomeni Siwe, Odile Baponwa, Sidiki Aboubakar, Joseph Fleurie Emakoua, Paul Vernyuy Tan, Palanisamy Nallasamy   +8 more
wiley   +1 more source

Unveiling New Insights Into Faba Bean Sensitivity and Genetic Responses to the Mutagen Agent EMS (Ethyl Methanesulfonate)

International Journal of Agronomy, Volume 2025, Issue 1, 2025.
Mutagenesis breeding via ethyl methanesulfonate (EMS) has been successfully used in faba bean to improve some economically important traits. However, there is a knowledge gap of the factors/mechanisms related to its sensitivity/tolerance to EMS treatment toxicity.
Oumaima Chetto, Loubna Belqadi, Mohamed Kouighat, Etienne Bucher, Mohamed El Fechtali, Rokhaya Imelda Ndiaye, Abdelghani Nabloussi, Mehdi Rahimi   +7 more
wiley   +1 more source

Study on Antiseepage Measures for Earth‐Rock Dam Reservoir in Super‐Intense Karst Area: Research on Curtain Grouting Scheme for Comprehensive Seepage Prevention

Structural Control and Health Monitoring, Volume 2025, Issue 1, 2025.
Constructing reservoirs in karst regions is a challenge that dam engineers around the world are very unwilling to face. The antiseepage of reservoirs is one of the urgent problems to be solved in the construction of reservoirs in karst regions.
Mingming Wang, Chunying Shen, Jihong Duan, Ming Ye, Qiang Xu, Michael Krommer   +5 more
wiley   +1 more source

Short‐ and Long‐Term Seismic Velocity Variations and Strain Evolution at Ischia (Italy): Implications for Dynamics of the Hydrothermal System

Geophysical Research Letters, Volume 51, Issue 23, 16 December 2024.
Abstract In active volcanic systems, the elevated pressurization of fluids and the movement of molten materials influence the stress state and mechanical behavior of rocks, but the direct measurement of these processes and the related evolution of rocks properties is difficult.
Stefania Tarantino, Piero Poli, Maurizio Vassallo, Nicola D’Agostino   +3 more
wiley   +1 more source