Results 1 to 10 of about 25,789 (212)

Endobronchial Valve Treatment in Emphysema Patients with a Very Low DLCO [PDF]

Respiration, 2020
Background: For selected patients with severe emphysema, bronchoscopic lung volume reduction with endobronchial valves (EBV) is recognized as an additional treatment option.
Marlies van Dijk, Jorine E. Hartman, Karin Klooster, Nick H.T. ten Hacken, Huib A.M. Kerstjens, Dirk‐Jan Slebos   +5 more
openalex   +2 more sources

Participation of the miR-22-HDAC4-DLCO Axis in Patients with COPD by Tobacco and Biomass [PDF]

Biomolecules, 2019
Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation and systemic inflammation. The main causes of COPD include interaction between genetic and environmental factors associated with tobacco smoking (COPD-TS) and/or exposure
Yadira Velasco-Torres, Vı́ctor Ruiz, Martha Montaño, Rogelio Pérez‐Padilla, Ramcés Falfán‐Valencia, Julia Pérez‐Ramos, Oliver Pérez-Bautista, Carlos Ramos   +7 more
openalex   +2 more sources

DLCO versus DLCO/VA as predictors of pulmonary gas exchange [PDF]

Respiratory Medicine, 2007
The diffusing capacity of the lung is usually reported as both the diffusing capacity (DLCO) and the diffusing capacity divided by the alveolar volume (DLCO/VA). However, it is unclear which measure to use when interpreting pulmonary gas exchange. We therefore conducted this study to determine whether the DLCO or the DLCO/VA is a better predictor of ...
Kaminsky, David A., Whitman, Todd, Callas, Peter W.   +2 more
openaire   +3 more sources

Time-based understanding of DLCO and DLNO

Respiratory Physiology & Neurobiology, 2016
Capture of CO and NO by blood requires molecules to travel by diffusion from alveolar gas to haemoglobin molecules inside RBCs and then to react. One can attach to these processes two times, a time for diffusion and a time for reaction. This reaction time is known from chemical kinetics and, therefore, constitutes a unique physical clock.
Kang, Min-Yeong, Sapoval, Bernard
openaire   +3 more sources

Predictive value of isolated DLCO reduction in systemic sclerosis patients without cardio-pulmonary involvement at baseline

Reumatismo, 2016
Impaired diffusing capacity of the lung for carbon monoxide (DLCO) was frequently observed in systemic sclerosis (SSc) patients, generally related to the presence of interstitial lung disease (ILD) and/or pulmonary arterial hypertension (PAH).
Michele Colaci, D. Giuggioli, Marco Sebastiani, Andreina Manfredi, Federica Lumetti, Fabrizio Luppi, Stefania Cerri, Claudio Ferri   +7 more
openalex   +3 more sources

Lower DLco% identifies exercise pulmonary hypertension in patients with parenchymal lung disease referred for dyspnea

Pulmonary Circulation, 2019
Exercise pulmonary hypertension is an underappreciated form of physical limitation related to early pulmonary vascular disease. A low diffusing capacity of lungs for carbon monoxide (DLco) can be seen in patients with resting pulmonary hypertension as ...
Richard H. Zou, William D. Wallace, Mehdi Nouraie, Stephen Y. Chan, Michael G. Risbano   +4 more
openalex   +2 more sources

Reduced Dlco in GOLD I COPD [PDF]

Chest, 2021
Richard H. Zou, Jessica Bon
openaire   +2 more sources

DLco, Kco and FVC/DLco in suspected systemic sclerosis-associated pulmonary hypertension: Insights from the ASPIRE registry

ERJ Open Research
Objectives There are limited data comparing parameters reflecting gas transfer used to assess the likelihood of pulmonary hypertension (PH) in patients with systemic sclerosis (SSc) and regarding the impact of transitioning to Global Lung Initiative (GLI)-predicted values.
Howard Smith, A.A. Roger Thompson, Mohammed Akil, Samer Alabed, Catherine Billings, Athanasios Charalampopoulos, Krit Dwivedi, Charlie A. Elliot, Abdul Hameed, Ashraful Haque, Neil Hamilton, Catherine Hill, Judith Hurdman, Rachael Kilding, Kar-Ping Kuet, Smitha Rajaram, Alexander M.K. Rothman, Ian Smith, Andrew J. Swift, David G. Kiely, Robin Condliffe   +20 more
openaire   +3 more sources

Relationship of Pulmonary Artery to Aorta Ratio With Pulmonary Vascular Resistance, Compliance, and Outcomes in COPD and Interstitial Lung Disease in PVDOMICS. [PDF]

Pulm Circ
ABSTRACT Noninvasive imaging markers may be helpful in identifying higher‐risk patients with various lung diseases. Pulmonary artery to aorta ratio (PA/A ratio) on computed tomography (CT) is an indicator of pulmonary hypertension, but its relationship with other hemodynamic, imaging, and physiologic measurements, functional status, and outcomes ...
Jankowich MD, Borgia M, Lempel J, Desanti E, Renapurkar R, Morrison AR, Choudhary G, Rounds SI.   +7 more
europepmc   +2 more sources

Anti-Eukaryotic Initiation Factor 2B-Positive Systemic Sclerosis-Associated Interstitial Lung Disease With Progressive Fibrosis: A Case Report. [PDF]

Respirol Case Rep
We report the case of a patient with anti‐eIF2B‐positive SSc‐ILD managed with stepwise mycophenolate titration and subsequent nintedanib addition, accompanied by serial biomarkers and clinical follow‐up to help delineate the therapeutic course within this rare serological phenotype.
Ikeda H, Tachikawa R, Sasada T, Sumitomo S.   +3 more
europepmc   +2 more sources