Background: DLco remains one of the most commonly performed tests in the pulmonary lab. An isolated reduction in DLco is a unique abnormality with specific differentials when evaluating a patient with dyspnea. There remains a significant misunderstanding
Ahmad Raza +4 more
doaj +3 more sources
DLCO versus DLCO/VA as predictors of pulmonary gas exchange [PDF]
The diffusing capacity of the lung is usually reported as both the diffusing capacity (DLCO) and the diffusing capacity divided by the alveolar volume (DLCO/VA). However, it is unclear which measure to use when interpreting pulmonary gas exchange. We therefore conducted this study to determine whether the DLCO or the DLCO/VA is a better predictor of ...
David A. Kaminsky +2 more
openalex +4 more sources
Effect of alveolar volume on the interpretation of single breath DlCO
Single-breath carbon monoxide diffusing capacity in the whole lung (DLCO) and per unit alveolar volume (DLCO/VA), as expressed in percentage of normal values, gave discordant results when VA of the patients was abnormal. It was hypothesized that normal reference values were inappropriate to interpret data collected in such patients.
A. Frans +4 more
openalex +4 more sources
Relevance of partitioning DLCO to detect pulmonary hypertension in systemic sclerosis. [PDF]
We investigated whether partitioning DLCO into membrane conductance for CO (DmCO) and pulmonary capillary blood volume (Vcap) was helpful in suspecting precapillary pulmonary (arterial) hypertension (P(A)H) in systemic sclerosis (SSc) patients with or ...
Nadia Sivova +16 more
doaj +6 more sources
Relationship between diffusion capacity and small airway abnormality in COPDGene [PDF]
Impaired single breath carbon monoxide diffusing capacity (DLCO) is associated with emphysema. Small airways disease (SAD) may be a precursor lesion to emphysema, but the relationship between SAD and DLCO is undescribed. We hypothesized that in mild COPD,
Rachel N. Criner +12 more
doaj +3 more sources
DLCO in HIV Patients and Their Association with CD4 and VL [PDF]
Tianjiao Xue +11 more
openalex +3 more sources
Measurement of gas exchange surface area from DLNO and DLCO
The estimated diffusion coefficients for nitric oxide and carbon monoxide in human plasma and red cells can be inserted into the equations for Fick's 1st and 2nd laws. The surface area of the alveolar membrane and exposed red cells can then be calculated from DLNO and DLCO (in hyperoxia).
Colin Borland
openalex +3 more sources
The diffusing capacity of the lungs for carbon monoxide - an independent predictor of interstitial lung disease in patients with rheumatoid arthritis - results of a prospective study [PDF]
Background. The diffusing capacity of the lungs for carbon monoxide (DLCO) represents the most sensitive independent factor for highlighting the interstitial lung disease associated with rheumatoid arthritis (RA-ILD).
Maria-Luciana Anton +4 more
doaj +1 more source
Background Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities, usually caused by ...
Hamdy M Abd-Allah +3 more
doaj +1 more source
Predictors of fatigue severity in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort. [PDF]
ObjectivesLongitudinal studies examining the baseline predictors of fatigue in SSc have not been reported. Our objectives were to examine the course of fatigue severity over time and to identify baseline clinical, demographic, and psychosocial predictors
Assassi, Shervin +10 more
core +17 more sources

