Predictors of Diffusing Capacity in Children With Sickle Cell Disease: A Longitudinal Study
Background: Gas exchange abnormalities in Sickle Cell Disease (SCD) may represent cardiopulmonary deterioration. Identifying predictors of these abnormalities in children with SCD (C-SCD) may help us understand disease progression and develop informed ...
Pritish Mondal +4 more
doaj +1 more source
Time-based understanding of DLCO and DLNO
Capture of CO and NO by blood requires molecules to travel by diffusion from alveolar gas to haemoglobin molecules inside RBCs and then to react. One can attach to these processes two times, a time for diffusion and a time for reaction. This reaction time is known from chemical kinetics and, therefore, constitutes a unique physical clock.
Bernard Sapoval, Min-Yeong Kang
openaire +3 more sources
Characteristics of the elderly in high - resolution computed tomography lung densitometry [PDF]
To determine the characteristics of the elderly in high - resolution computed tomography (HRCT) lung densitometry, mean lung density (MLD) and relative area of the lungs showing attenuation values less than -950 HU (RA(950)) on HRCT were evaluated in ...
Ashida, Kozo +9 more
core +1 more source
Amiodarone-Induced Pulmonary Toxicity - A Frequently Missed Complication. [PDF]
IntroductionAmiodarone is often used in the suppression of tachyarrhythmias. One of the more serious adverse effects includes amiodarone pulmonary toxicity (APT).
Dang, Natasha +4 more
core +2 more sources
Endobronchial Valve Treatment in Emphysema Patients with a Very Low DLCO [PDF]
<b><i>Background:</i></b> For selected patients with severe emphysema, bronchoscopic lung volume reduction with endobronchial valves (EBV) is recognized as an additional treatment option. In most trials investigating EBV treatment, patients with a very low diffusing capacity (DLCO) were excluded from participation.
Marlies van Dijk +5 more
openaire +3 more sources
The 6 minute walk in idiopathic pulmonary fibrosis: longitudinal changes and minimum important difference [PDF]
The response characteristics of the 6 minute walk test (6MWT) in studies of idiopathic pulmonary fibrosis (IPF) are only poorly understood, and the change in walk distance that constitutes the minimum important difference (MID) over time is ...
Behr, Jürgen +6 more
core +1 more source
Prediction equations for diffusing capacity (transfer factor) of lung for North Indians
Background: Prediction equations for diffusing capacity of lung for carbon monoxide (DLCO), alveolar volume (VA), and DLCO/VA using the current standardization guidelines are not available for Indian population.
Sunil Kumar Chhabra +2 more
doaj +1 more source
P267 Dlco predicts disease severity and mortality in bronchiectasis [PDF]
Background Few studies have assessed the role of lung diffusing capacity (DLCO%) in bronchiectasis. We sought to examine the relationship between DLCO% and clinical and radiological variables in a well-defined population of bronchiectasis patients to determine its potential prognostic significance and compare with FEV1%.
Robert Rutherford +5 more
openaire +1 more source
Nintedanib for systemic sclerosis–associated interstitial lung disease [PDF]
BackgroundInterstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been shown to have antifibrotic and antiinflammatory effects ...
Alves, Margarida +16 more
core +3 more sources
Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database. [PDF]
Racial differences exist in the severity of systemic sclerosis (SSc). To enhance our knowledge about SSc in African Americans, we established a comprehensive clinical database from the largest multicenter cohort of African American SSc patients assembled
Boin, Francesco +28 more
core +1 more source

