Predictors of lung function test severity and outcome in systemic sclerosis-associated interstitial lung disease. [PDF]
Systemic sclerosis-related interstitial lung disease (SSc-ILD) is the leading cause of death in SSc. In this study, we aimed to describe the baseline severity and evolution of forced vital capacity (FVC) and diffusing capacity for carbon monoxide (DLCO ...
Noémie Le Gouellec +13 more
doaj +1 more source
The 6 minute walk in idiopathic pulmonary fibrosis: longitudinal changes and minimum important difference [PDF]
The response characteristics of the 6 minute walk test (6MWT) in studies of idiopathic pulmonary fibrosis (IPF) are only poorly understood, and the change in walk distance that constitutes the minimum important difference (MID) over time is ...
Behr, Jürgen +6 more
core +1 more source
Serum uric acid as a marker of microvascular damage in systemic sclerosis patients [PDF]
Background: Microvascular damage of skin and internal organs is a hallmark of systemic sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial dysfunction.
Amoroso, Antonio +9 more
core +1 more source
Predictors of Diffusing Capacity in Children With Sickle Cell Disease: A Longitudinal Study
Background: Gas exchange abnormalities in Sickle Cell Disease (SCD) may represent cardiopulmonary deterioration. Identifying predictors of these abnormalities in children with SCD (C-SCD) may help us understand disease progression and develop informed ...
Pritish Mondal +4 more
doaj +1 more source
Nintedanib for systemic sclerosis–associated interstitial lung disease [PDF]
BackgroundInterstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been shown to have antifibrotic and antiinflammatory effects ...
Alves, Margarida +16 more
core +3 more sources
Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database. [PDF]
Racial differences exist in the severity of systemic sclerosis (SSc). To enhance our knowledge about SSc in African Americans, we established a comprehensive clinical database from the largest multicenter cohort of African American SSc patients assembled
Boin, Francesco +28 more
core +1 more source
Prediction equations for diffusing capacity (transfer factor) of lung for North Indians
Background: Prediction equations for diffusing capacity of lung for carbon monoxide (DLCO), alveolar volume (VA), and DLCO/VA using the current standardization guidelines are not available for Indian population.
Sunil Kumar Chhabra +2 more
doaj +1 more source
Amiodarone-Induced Pulmonary Toxicity - A Frequently Missed Complication. [PDF]
IntroductionAmiodarone is often used in the suppression of tachyarrhythmias. One of the more serious adverse effects includes amiodarone pulmonary toxicity (APT).
Dang, Natasha +4 more
core +2 more sources
The inspiratory capacity/total lung capacity ratio as a predictor of survival in an emphysematous phenotype of chronic obstructive pulmonary disease. [PDF]
BackgroundForced expiratory volume in 1 second (FEV1) grades severity of COPD and predicts survival. We hypothesize that the inspiratory capacity/total lung capacity (IC/TLC) ratio, a sensitive measure of static lung hyperinflation, may have a ...
Balfe, David +4 more
core +1 more source
Adverse reactions of amiodarone [PDF]
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo +5 more
core +1 more source

