Results 51 to 60 of about 17,391 (234)

Serum Type I Interferon Score for Prediction of Clinically Meaningful Disease Progression in Limited Cutaneous Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To assess the value of serum type I interferon (IFN) score in predicting clinically meaningful progression in limited cutaneous systemic sclerosis (lcSSc) using a novel composite endpoint adopted from the MINIMISE clinical trial. Methods A retrospective, longitudinal lcSSc cohort was identified within a national, multicenter observational ...
Stefano Di Donato, Rebecca Ross, Ranjitha Karanth, Vishal Kakkar, Enrico De Lorenzis, Lesley‐Anne Bissell, Kristina Clark, Philip Yee, Christopher P. Denton, Francesco Del Galdo   +9 more
wiley   +1 more source

Mono and combination therapies in pulmonary arterial hypertension patients with comorbidities: A COMPERA analysis

ESC Heart Failure, EarlyView.
AIM This analysis provides a comparison of the efficacy of initial mono and combination therapy in patients with PAH and cardiovascular comorbidities or with risk factors of HFpEF (heart failure with preserved ejection fractioin).METHOD Data from the European COMPERA registry were used for a matched pair analysis.
Dirk Skowasch, Christine Pausch, Doerte Huscher, David Pittrow, Judith Wede, Fabian Kreimendahl, Stephan Rosenkranz, Stephan Beckmann, Matthias Held, Ekkehard Grünig, H. Ardeschir Ghofrani, Hans Klose, Andris Skride, Michael Halank, Stefan Stadler, Marion Delcroix, Anton Vonk‐Noordegraaf, Ralf Ewert, Grzegorz Kopec, Marius M. Hoeper, Karen M. Olsson   +20 more
wiley   +1 more source

Lower DLco% identifies exercise pulmonary hypertension in patients with parenchymal lung disease referred for dyspnea

Pulmonary Circulation, 2020
Exercise pulmonary hypertension is an underappreciated form of physical limitation related to early pulmonary vascular disease. A low diffusing capacity of lungs for carbon monoxide (DLco) can be seen in patients with resting pulmonary hypertension as ...
Richard H. Zou, William D. Wallace, S. Mehdi Nouraie, Stephen Y. Chan, Michael G. Risbano   +4 more
doaj   +1 more source

Lung diffusing capacity for nitric oxide and carbon monoxide following mild‐to‐severe COVID‐19

Physiological Reports, 2021
A decreased lung diffusing capacity for carbon monoxide (DLCO) has been reported in a variable proportion of subjects over the first 3 months of recovery from severe coronavirus disease 2019 (COVID‐19).
Giovanni Barisione, Vito Brusasco
doaj   +1 more source

Result of one-year, prospective follow-up of intensive care unit survivors after SARS-CoV-2 pneumonia

Annals of Intensive Care, 2022
Key Points The most interesting findings were that most patients showed an improvement in their DLCO at 3, 6, and 12 months, and all patients but one who normalized their DLCO did not deteriorate afterwards. Only 11% of patients had persistent impairment
Guillaume Eberst, Fréderic Claudé, Lucie Laurent, Aurelia Meurisse, Pauline Roux-Claudé, Cindy Barnig, Dewi Vernerey, Sophie Paget-Bailly, Kevin Bouiller, Catherine Chirouze, Julien Behr, Franck Grillet, Ophélie Ritter, Sinan Karaer, Sébastien Pili-Floury, Hadrien Winiszewski, Emmanuel Samain, Pierre Decavel, Gilles Capellier, Virginie Westeel   +19 more
doaj   +1 more source

Functional Pulmonary Imaging

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The aging of the world population gave rise to an increased prevalence of many lung diseases, with chronic obstructive pulmonary disease now ranking as the third‐leading cause of death according to the World Health Organization. To diagnose lung disease, a thorough assessment of lung function is essential since it may reveal unique signatures ...
Agilo L. Kern, Filip Klimeš, Andreas Voskrebenzev, Hoen‐Oh Shin, Jens Vogel‐Claussen   +4 more
wiley   +1 more source

An Integrated Assessment Approach for Socio‐Economic Implications of the Desert Locust in Eastern Africa

Earth's Future
Desert locust (Schistocerca gregaria) infestations cause significant damage to crops and pastureland, impeding food security and livelihoods globally.
Bonoukpoè Mawuko Sokame, Komi Mensah Agboka, Emily Kimathi, Bester Tawona Mudereri, Elfatih M. Abdel‐Rahman, Tobias Landmann, Mwesigwa Moses Rwaheru, Osman Abdalla, Moses M. Mafabi, Louis Mitondo Lubango, Henri E. Z. Tonnang   +10 more
doaj   +1 more source

Safety and Efficacy of Salvage Surgery after Treatment With Immune‐Checkpoint Adjuvant Inhibitors for Advanced Non‐Small Cell Lung Cancer: A Multicentric Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Objective In advanced non‐small cell lung cancer (NSCLC), immune‐checkpoint inhibitors (ICIs) can achieve significant clinical responses. This raises the question of whether to consider salvage surgery as a curative treatment option. Few case series reported encouraging results in terms of pathological response.
Marco Schiavon, Giorgio Cannone, Luca Bertolaccini, Filippo Tommaso Gallina, Federica Pezzuto, Giulia Lorenzoni, Francesco Facciolo, Lorenzo Spaggiari, Fiorella Calabrese, Federico Rea, Giulia Pasello, The Lung Oncology Group   +11 more
wiley   +1 more source

FVC/DLCO identifies pulmonary hypertension and predicts 5-year all-cause mortality in patients with COPD

European Journal of Medical Research, 2023
Background Pulmonary hypertension (PH) is a common complication of chronic obstructive pulmonary disease (COPD). However, it is unknown whether the ratio of forced vital capacity (FVC) to diffusing lung capacity for carbon monoxide (DLCO) can identify PH
Yuer Li, Rui Zhang, Hu Shan, Wenhua Shi, Xiaoli Feng, Haijuan Chen, Xia Yang, Yali Li, Jie Zhang, Ming Zhang   +9 more
doaj   +1 more source

Comparing Comorbidity Indices to Predict Survival After Pediatric Hematopoietic Stem Cell Transplantation for Nonmalignant Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Hematopoietic stem cell transplantation (HCT) is a potentially curative treatment for children with hematological or immunological disorders. However, treatment‐related morbidity and mortality remain concerning. Various comorbidity indices are currently used to assess the risk of complications following pediatric HCT.
Roos Lotte Alexandra Bukman, Anne B. Verbeek, Arjan C. Lankester, Erik G. J. von Asmuth, Emilie Pauline Buddingh   +4 more
wiley   +1 more source