Results 71 to 80 of about 25,789 (212)

Isolated Anti‐SS‐A Antibody Seropositivity as a Poor Prognostic Factor in Systemic Sclerosis: Insights From a Cohort of 307 Cases

open access: yesThe Journal of Dermatology, Volume 53, Issue 1, Page 41-53, January 2026.
ABSTRACT Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. Anti‐SS‐A antibodies (anti‐SSA) have been reported to confer severe clinical manifestations in some Western and Japanese cohorts. We aimed to determine whether anti‐SSA seropositivity affects clinical outcomes in Japanese patients. We
Nana Ishida   +4 more
wiley   +1 more source

Non‐Small Cell Lung Cancer Patients With Tumors ≤ 2 Cm Are Suitable for Wedge Resection or Segmentectomy: A Real‐World Study

open access: yesThoracic Cancer, Volume 17, Issue 1, January 2026.
Wedge resection is an optimal choice for NSCLCs ≤ 2 cm, especially for GGO‐dominant tumors. However, segmentectomy is more appropriate when the CTR is > 0.25. ABSTRACT Background The role of wedge resection in the treatment of non‐small cell lung cancer (NSCLC) with solid components ≤ 2 cm remains controversial.
Yuetian Pan   +4 more
wiley   +1 more source

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa   +7 more
wiley   +1 more source

Fibroblast‐driven MMP‐9/TIMP‐1 imbalance in bronchoalveolar lavage reflects fibrotic progression in interstitial lung disease

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Abstract Background Interstitial lung diseases (ILDs) are characterized by progressive fibrosis, in which extracellular matrix remodelling is regulated by matrix metalloproteinases (MMPs) and their inhibitors (TIMPs). The MMP‐9/TIMP‐1 balance has been implicated in fibrogenesis, but its role in human ILD remains incompletely defined.
Maria Bertolotto   +13 more
wiley   +1 more source

Lobe‐Specific Variability in Postoperative Pulmonary Function in Lung Cancer Patients: A Longitudinal Analysis and Comparison With Traditional Predictive Models

open access: yesRespirology, Volume 31, Issue 1, Page 62-72, January 2026.
We evaluated lobe‐specific lung function recovery at 6 months after lobectomy in 419 early‐stage NSCLC patients. The surgical approach, right upper lobectomy compared with right lower lobectomy, and reduced postoperative physical activity were associated with poor lung function recovery. See related editorial ABSTRACT Background and Objective Lobectomy
Yeong Jeong Jeon   +8 more
wiley   +1 more source

Preoperative DLCO predicts severe early complications after liver transplantation

open access: yesRespiratory Medicine and Research
Severe early complications are common after liver transplantation (LT) and are a key determinant of LT-related morbidity and mortality. The aim of this study was to assess whether lung function measured in the pre-operative period predicted complicated outcomes in the first month after LT.Patients with mild-to-moderate liver disease (Model for End ...
Xing Li   +5 more
openaire   +2 more sources

DLCO and exercise intolerance_Online supplement_JAP_July 16 2019.docx

open access: yes, 2019
This is a file containing online data supplement for a manuscript submitted to JAP. It contains text, 2 tables and 3 figures.
Amany Elbehairy   +8 more
openaire   +1 more source

AB0550 DIFFUSING CAPACITY OF THE LUNG FOR CARBON MONOXIDE (DLCO) VS FORCED VITAL CAPACITY (FVC): SYSTEMATIC LITERATURE REVIEW AND META-ANALYSIS TO EXAMINE THEIR ABILITY TO MEASURE CHANGE IN CLINICAL TRIALS IN SYSTEMIC SCLEROSIS (SSC) [PDF]

open access: bronze, 2020
Silvia Bellando-Randone   +10 more
openalex   +1 more source

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