Results 51 to 60 of about 55,611 (129)

Revisiting Traceability of Vegetable Fresh‐Products in the EU: Why Blockchain Does (Not) Work?

open access: yesInternet Technology Letters, EarlyView.
ABSTRACT Food safety is paramount for a healthy society. Traceability provides the means for a rapid response to any type of food‐related problem at any stage of the supply chain. This study delves into the application of blockchain technology in tracking vegetable products within the European Union's regulatory framework.
I. Tasic   +4 more
wiley   +1 more source

The Combination of Active‐Targeted Photodynamic Therapy and Photoactivated Chemotherapy for Enhanced Cancer Treatment

open access: yesJournal of Biophotonics, EarlyView.
Photoactivated chemotherapy (PACT), an oxygen‐independent light‐based therapy, utilizes chemotherapeutic regimens that remain inert until exposed to light, allowing target‐specific activation while minimizing off‐target toxicity. The integration of these techniques has the potential to improve selectivity and yield synergistic cytotoxic effects that ...
Nkune Williams Nkune, Heidi Abrahamse
wiley   +1 more source

A Systematic Evaluation of the Dosing Regimens for Approved Targeted Therapies and Immune Checkpoint Inhibitors in Metastatic Renal Cell Carcinoma From a Project OPTIMUS Perspective

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Targeted therapies and immune checkpoint inhibitors (ICIs) have significantly improved survival outcomes in metastatic renal cell carcinoma (mRCC) but are often associated with high rates of adverse events, leading to dose reductions or treatment discontinuation.
Zhiyuan Tan   +4 more
wiley   +1 more source

State of Social Marketing in Malaysia: Challenges and Reflections of a Multinethnic, Multiligual and Multiultural Nation. [PDF]

open access: yes
© 2024 Academy of Marketing. This is the accepted manuscript version of a conference paper which has been published in final form at https://academyofmarketing.org/am2024-conference/Malaysia, a nation that celebrates the rich tapestry of Asian cultures ...
DLT, Ong
core  

Evaluation of exposure‐response‐safety relationship of model‐informed low‐dose 500 mg abiraterone acetate in prostate cancer patients

open access: yes
Cancer Communications, EarlyView.
Edmund Chiong   +15 more
wiley   +1 more source

Phase I/II Trial of Perioperative Avelumab in Combination With Chemoradiation in the Treatment of Stage II/III Resectable Esophageal and Gastroesophageal Junction Cancer

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Standard treatment of patients with stage II/III esophageal or gastroesophageal junction (E/GEJ) cancer involves neoadjuvant chemoradiation (nCRT), resection, and immunotherapy. Our trial evaluated the addition of perioperative avelumab to standard treatments.
Nataliya V. Uboha   +15 more
wiley   +1 more source

How I Approach Ethical Considerations for Pediatric Phase I CAR T‐Cell Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Phase I trials of chimeric antigen receptor (CAR) T cells have shown remarkable promise in pediatric B‐cell malignancies. Such outcomes have shifted expectations for other phase I CAR T‐cell trials to have high response rates. The juxtaposition of high expectations, uncertain outcomes, and potential for life‐threatening toxicities raises ...
Sarah W. Peters   +6 more
wiley   +1 more source

Postmarketing Assessment of Antibody–Drug Conjugates: Proof‐of‐Concept Using Model‐Based Meta‐Analysis and a Clinical Utility Index Approach

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Antibody–drug conjugates (ADCs) are a promising class of targeted cancer therapies. However, they need careful dose optimization to maximize effectiveness and minimize side effects. Sometimes, safety issues may only become apparent after approval, so ongoing evaluation is important.
Innocent Gerald Asiimwe   +6 more
wiley   +1 more source

On‐Stage Degradation of Solar Cells Studied Using Capacitance Transient and Luminescence Spectroscopies

open access: yesphysica status solidi (a), EarlyView.
Light‐ and temperature‐induced degradation (LeTID) of Si‐based solar cells is studied using low‐temperature photo‐ and electroluminescence and deep‐level transient spectroscopy during the on‐stage degradation/regeneration process. Based on the obtained and previously reported data, LeTID reflects hydrogen dynamics between extended defects present in ...
Teimuraz Mchedlidze   +5 more
wiley   +1 more source

Advanced Characterization of the Spatial Variation of Moiré Heterostructures and Moiré Excitons

open access: yesSmall, EarlyView.
In this review, the authors discuss recent advanced tools to characterize and understand the effects of spatial variation and inhomogeneities in moiré heterostructures over multiple length scales. Emphasis is placed on correlating the impact of twist angle misalignment, nano‐scale disorder, and atomic relaxation on the moiré potential and moiré ...
Alberto de la Torre   +3 more
wiley   +1 more source

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