Results 131 to 140 of about 3,658,235 (282)

Mechanochemical Piezoelectric Catalysis: Advancing the Hydrogenation of Alkenes

open access: yesAdvanced Science, EarlyView.
This study presents mechanochemical piezoelectric catalysis for alkene hydrogenation, eliminating the need for transition metals, H2, and solvents. The method effectively hydrogenates diverse activated and unactivated alkenes and shows potential for modifying bioactive molecules in pharmaceuticals.
Zixi Ai   +5 more
wiley   +1 more source

Lightweight, Elastic Ceramic Fabrics for Broadband Electromagnetic Absorption and High Temperature Thermal Insulation

open access: yesAdvanced Science, EarlyView.
This study reports lightweight, elastic ceramic fabrics with broadband electromagnetic absorption (EAB = 9.8 GHz) and high‐temperature thermal insulation, enabled by precise microstructural control during ultrafast high‐temperature sintering (UHS), which induces the precipitation of defect‐rich t‐ZrO2 nanograins and turbostratic C nanoclusters.
Jiahao Yang   +9 more
wiley   +1 more source

Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus

open access: yesAdvanced Science, EarlyView.
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Matteo Tollemeto   +5 more
wiley   +1 more source

Ti‐Doping Activates Adjacent Zr Sites in Bimetallic MOFs for Cooperative Phospholipid Removals in Human Biomonitoring

open access: yesAdvanced Science, EarlyView.
Ti‐doped Zr/Ti bimetallic MOFs activate neighboring Zr sites to selectively capture phospholipids from serum through cooperative interactions. In nontargeted screening, the material minimizes matrix interference, expands detectable feature coverage, and enables broad recovery of diverse chemical hazards, providing a powerful cleanup strategy for LC ...
Yanmin Liang   +5 more
wiley   +1 more source

Influence of artificial light on prevalence of DMF index in institutionalized adolescents

open access: yes, 2008
Objetivo: Comparar os valores do índice CPOD verificados por meio do exame das condições dentárias sob iluminação natural e artificial. Metodologia: A população estudada foi composta por adolescentes da Instituição Fundação Mirim de Araçatuba-SP, na faixa etária de 15 a 17 anos, selecionados aleatoriamente (n=38).
Moimaz, Suzely Adas Saliba   +3 more
openaire   +1 more source

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu   +10 more
wiley   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

open access: yesAdvanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori   +10 more
wiley   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

open access: yesAdvanced Science, EarlyView.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao   +10 more
wiley   +1 more source

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