Results 41 to 50 of about 63,760 (323)

Similarities and Differences of International Practices and Procedures for the Regulation for Active Substance Master Files/Drug Master Files of Human Use: Moving Toward Regulatory Convergence

Journal of Pharmacy & Pharmaceutical Sciences, 2016
Purpose. A gap analysis survey of international practices for Active Substance Master Files (ASMFs)/Drug Master Files (DMFs) of human use was conducted as a project of the ASMF/DMF working group of the International Generic Drug Regulators Pilot (IGDRP ...
Maki Matsuhama, Tomoko Takishita, Ryosuke Kuribayashi, Kazunori Takagi, Rika Wakao, Kenichi Mikami   +5 more
doaj   +1 more source

Apache Mahout’s k-Means vs. fuzzy k-Means performance evaluation [PDF]

, 2016
(c) 2016 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or ...
Barolli, Leonard, Bogza, Adriana, Caballé Llobet, Santiago, Xhafa Xhafa, Fatos   +3 more
core   +1 more source

Prognostic factors in adult soft tissue sarcoma treated with surgery combined with radiotherapy: a retrospective single-center study on 164 patients

Rare Tumors, 2013
The aim of the present study is to assess the disease profile, outcome and prognostic factors in patients treated with surgery combined with radiotherapy (RT), with or without chemotherapy (CXT), for soft-tissue sarcoma (STS) in a multidisciplinary ...
Ling Cai, René-Olivier Mirimanoff, Elyazid Mouhsine, Louis Guillou, Pierre-Francois Leyvraz, Serge Leyvraz, Beatrice Gay, Oscar Matzinger, Mahmut Ozsahin, Abderrahim Zouhair   +9 more
doaj   +1 more source

Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages [PDF]

, 2018
Background: As crucial regulators of the immune response against pathogens, macrophages have been extensively shown also to be important players in several diseases, including cancer. Specifically, breast cancer macrophages tightly control the angiogenic
Blandino, Giovanni, Donzelli, Sara, Fazi, Francesco, Fontemaggi, Giulia, Gallo, Enzo, Iosue, Ilaria, Masciarelli, Silvia, Melucci, Elisa, Milano, Elisa, Mottolese, Marcella, Pruszko, Magdalena, Sacconi, Andrea, Terrenato, Irene, Zylicz, Alicja, Zylicz, Maciej   +14 more
core   +3 more sources

Oral health status in relation to nutritional status among institutionalized autistic children and adolescents in Baghdad city, Iraq

Journal of Baghdad College of Dentistry, 2017
Background: The autism spectrum disorder (ASD) describes a wide range of symptoms, including difficulty with social interaction and communication skills.
Ali Hadi F. , Nada Jafer MH. Radhi
doaj   +1 more source

A Model for the Analysis of Caries Occurrence in Primary Molar Tooth Surfaces [PDF]

, 2012
Recently methods of caries quantification in the primary dentition have moved away from summary ‘whole mouth’ measures at the individual level to methods based on generalised linear modelling (GLM) approaches or survival analysis approaches. However, GLM
Baelum V, Beck J, Bower E, Burnside G, Burnside G, Fejerskov O, Gilthorpe M, Gilthorpe M, Gilthorpe M, Hannigan A, Hopcraft M, Hujoel P, J. Stephenson, James P, Jones C, Leroy R, Leroy R, Levine R, Lindsey J, Mancl L, Mejare I, Pitts N, Ramirez O, Riley J, Rodrigues C, Selwitz R, Stephenson J, Stephenson J, Tickle M, Vanobbergen J   +29 more
core   +1 more source

The elevated preoperative platelet-to-lymphocyte ratio predicts poor prognosis in breast cancer patients

British Journal of Cancer, 2014
Background:The elevation of the platelet-to-lymphocyte ratio (PLR), an easily applicable blood test based on platelet and lymphocyte counts has been associated with poor prognosis in patients with different types of cancer. The present study was aimed to
S. Krenn-Pilko, U. Langsenlehner, E. Thurner, T. Stojaković, M. Pichler, A. Gerger, K. Kapp, T. Langsenlehner   +7 more
semanticscholar   +1 more source

Tumour-infiltrating lymphocytes predict response to definitive chemoradiotherapy in head and neck cancer

British Journal of Cancer, 2013
Background:We aimed to investigate the prognostic value of tumour-infiltrating lymphocytes’ (TILs) expression in pretreatment specimens from patients with head and neck squamous cell carcinoma (HNSCC) treated with definitive chemoradiotherapy (CRT ...
P. Balermpas, Y. Michel, J. Wagenblast, O. Seitz, C. Weiss, F. Rödel, C. Rödel, E. Fokas   +7 more
semanticscholar   +1 more source

Impact of time to local recurrence on the occurrence of metastasis in breast cancer patients treated with neoadjuvant chemotherapy: A random forest survival approach.

PLoS ONE, 2019
BackgroundWe studied the relationship between time to ipsilateral breast tumor recurrence (IBTR) and distant metastasis-free survival (DMFS) in patients with breast cancer treated by neoadjuvant chemotherapy (NAC).MethodsBetween 2002 and 2012, 1199 ...
Enora Laas, Anne-Sophie Hamy, Anne-Sophie Michel, Nabilah Panchbhaya, Matthieu Faron, Thanh Lam, Sophie Carrez, Jean-Yves Pierga, Roman Rouzier, Florence Lerebours, Jean-Guillaume Feron, Fabien Reyal   +11 more
doaj   +1 more source

Prognostic significance of a combined and controlled nutritional status score and EBV-DNA in patients with advanced nasopharyngeal carcinoma: a long-term follow-up study

Cancer Biology & Medicine, 2022
Objective: Several studies have reported that the controlling nutritional status (CONUT) score is a prognostic predictor for survival among patients with different types of cancer.
Hui Lu, Shanshan Guo, Liting Liu, Qiuyan Chen, Yujing Liang, Sailan Liu, Xuesong Sun, Qingnan Tang, Xiaoyun Li, Ling Guo, Haoyuan Mo, Linquan Tang, Haiqiang Mai   +12 more
doaj   +1 more source