Results 221 to 230 of about 13,815,827 (291)

Synthesis and Biological Evaluation of Well‐Defined M6P(n)‐Modified Glycopeptides for Targeted Protein Degradation

open access: yesChemistry – A European Journal, Volume 32, Issue 33, 1 September 2026.
A synthetic methodology has been developed to prepare multifunctional M6P and M6Pn ligands of different valency. The glycopeptides were conjugated to cetuximab and then examined to mediate cellular uptake of fluorescently labeled EGFRvIII. Only cetuximab modified by glycopeptides having 3 or 6 M6P or M6Pn residues demonstrated greater uptake.
Patrycja Lenartowicz   +6 more
wiley   +1 more source

Histone acetylation promotes FKBP5 to increase reparative dentin formation in pulp repair. [PDF]

open access: yesStem Cells Transl Med
Duan S   +7 more
europepmc   +1 more source

Executive Function and Epigenetic Markers in Youth Exposed to Family and Community Violence in Childhood

open access: yesDevelopmental Psychobiology, Volume 68, Issue 5, September 2026.
ABSTRACT Although exposure to violence has been linked to executive functioning impairments, the biological mechanisms underlying this association remain unclear. This study examined CpG sites associated with executive functions in 78 young adults and their links to family (psychological and physical) and community violence during childhood. The scales
Renata Queiroz Ramos   +6 more
wiley   +1 more source

Pumping Venom: Valvilli Architecture in Diacamma (Hymenoptera: Formicidae) and Implications for Stinger Functionality

open access: yesJournal of Morphology, Volume 287, Issue 9, September 2026.
The insect stinger is among the best‐known venom‐delivery structures, yet its valvilli—paired flaps within the valve chamber—remain poorly understood. Using micro‐CT, histology, serial block‐face SEM and CLSM in the ant Diacamma nr. indicum, we show that the valvilli are not uniformly flexible flaps but are materially differentiated structures with ...
Alexandre Casadei‐Ferreira   +6 more
wiley   +1 more source

Real-world impact of treatment on growth in children with X-linked hypophosphatemia.

open access: yesJ Clin Endocrinol Metab
Fukumoto S   +12 more
europepmc   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang   +10 more
wiley   +1 more source

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