Results 261 to 270 of about 254,372 (361)

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

open access: yesAdvanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang   +27 more
wiley   +1 more source

Aux experts et relecteurs de DMS

open access: yesDistances et Médiations des Savoirs, 2017
Conseil scientifique de DMS
doaj   +1 more source

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

open access: yesAdvanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong   +14 more
wiley   +1 more source

CoV-UniBind: a unified antibody binding database for SARS-CoV-2. [PDF]

open access: yesBioinform Adv
Bhasin A   +6 more
europepmc   +1 more source

Probing the structure of ribosome assembly intermediates in vivo using DMS and hydroxyl radical footprinting

open access: bronze, 2016
Ryan M. Hulscher   +8 more
openalex   +2 more sources

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