Results 81 to 90 of about 256,976 (337)

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Dimethylsphingosine Regulates Intracellular pH and Ca2+ Human Monocytes

open access: yesJournal of Pharmacological Sciences, 2006
.: Dimethylsphingosine (DMS) was first reported as an inhibitor of protein kinase C and later has been used as a specific inhibitor of sphingosine kinase.
Eun-Hee Lee   +5 more
doaj   +1 more source

Air exposure of coral is a significant source of dimethylsulfide (DMS) to the atmosphere

open access: yesScientific Reports, 2016
Corals are prolific producers of dimethylsulfoniopropionate (DMSP). High atmospheric concentrations of the DMSP breakdown product dimethylsulfide (DMS) have been linked to coral reefs during low tides.
Frances E. Hopkins   +4 more
semanticscholar   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah   +8 more
wiley   +1 more source

The hidden reefs in foreign language teaching: on the presence and instruction of discourse markers in textbooks for teaching Polish as a foreign language

open access: yesGlottodidactica, 2019
Discourse markers (DMs), represented by words and phrases such as but, you know, moreover, have for many years been a widely discussed topic in linguistics in Poland and abroad.
Sandra Toffel
doaj   +1 more source

Excitonic instability in optically-pumped three-dimensional Dirac materials

open access: yes, 2017
Recently it was suggested that transient excitonic instability can be realized in optically-pumped two-dimensional (2D) Dirac materials (DMs), such as graphene and topological insulator surface states.
Balatsky, Alexander V., Pertsova, Anna
core   +1 more source

Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats [PDF]

open access: yes, 2017
Rationale Corticostriatal circuits are widely implicated in the top-down control of attention including inhibitory control and behavioural flexibility. However, recent neurophysiological evidence also suggests a role for thalamic inputs to striatum in
A Bari   +36 more
core   +2 more sources

Characterizing the Immunogenicity of DM-Sensitive and DM-Resistant Antigens

open access: yesBlood, 2018
Abstract Introduction: The separation of graft-versus-leukemia (GvL) effect from graft-versus-host-disease (GvHD) is a major objective after allogeneic stem cell transplantation. We recently described two types of endogenous HLA class II restricted antigens depending on their behavior towards HLA-DM.
Anna Luise Bernhardt   +5 more
openaire   +1 more source

Observational evidence for the formation of ocean DMS-derived aerosols during Arctic phytoplankton blooms

open access: yes, 2017
The connection between marine biogenic dimethyl sulfide (DMS) and the formation of aerosol particles in the Arctic atmosphere was evaluated by analyzing atmospheric DMS mixing ratios, aerosol particle size distributions and aerosol chemical composition ...
Ki‐Tae Park   +10 more
semanticscholar   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

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