Results 91 to 100 of about 60,289 (232)
Prokaryotic defense systems: Diversity and evolutionary adaptation
mLife, EarlyView.Abstract Bacteriophages and archaeal viruses are the most abundant biological entities on Earth. Through a long‐standing co‐evolutionary arms race, they have driven the emergence of a diverse repertoire of prokaryotic defense systems. This review summarizes these systems, highlighting their diverse antiviral mechanisms across distinct stages of viral ...
Changjialian Yang +3 more
wiley +1 more source
Ori-Finder 2, an integrated tool to predict replication origins in the archaeal genomes
Frontiers in Microbiology, 2014 DNA replication is one of the most basic processes in all three domains of cellular life. With the advent of the post-genomic era, the increasing number of complete archaeal genomes has created an opportunity for exploration of the molecular mechanisms ...
Hao eLuo, Chun-Ting eZhang, Feng eGao
doaj +1 more source
Structure and function of archaeal histones. [PDF]
PLoS Genetics, 2018 The genomes of all organisms throughout the tree of life are compacted and organized in chromatin by association of chromatin proteins. Eukaryotic genomes encode histones, which are assembled on the genome into octamers, yielding nucleosomes.
Bram Henneman +3 more
doaj +1 more source
Protein acetylation in archaea, bacteria, and eukaryotes [PDF]
, 2010 Proteins can be acetylated at the alpha-amino group of the N-terminal amino acid (methionine or the penultimate amino acid after methionine removal) or at the epsilon-amino group of internal lysines.
Lainio, Jarmo +1 more
core
Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates [PDF]
, 2013 Nonhomologous end-joining (NHEJ) pathways repair DNA double-strand breaks (DSBs) in eukaryotes and many prokaryotes, although it is not reported to operate in the third domain of life, archaea. Here, we describe a complete NHEJ complex, consisting of DNA
Bartlett, Edward +2 more
core +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas +3 more
wiley +1 more source
Archaeal histone-based chromatin structures regulate transcription elongation rates
Communications BiologyMany archaea encode and express histone proteins to compact their genomes. Archaeal and eukaryotic histones share a near-identical fold that permits DNA wrapping through select histone-DNA contacts to generate chromatin-structures that must be traversed ...
Breanna R. Wenck +3 more
doaj +1 more source
Frontiers in Microbiology, 2015 Restriction-modification (RM) systems have evolved to protect the cell from invading DNAs and are composed of two enzymes: a DNA methyltransferase and a restriction endonuclease. Although RM systems are present in both archaeal and bacterial genomes, DNA
Matthew eOuellette +3 more
doaj +1 more source
Methanogenic \u3cem\u3eArchaea\u3c/em\u3e and human periodontal disease [PDF]
, 2004 Archaea have been isolated from the human colon, vagina, and oral cavity, but have not been established as causes of human disease. In this study, we reveal a relationship between the severity of periodontal disease and the relative abundance of archaeal
Armitage, Gary C. +5 more
core +1 more source
Autophosphorylation of Archaeal Cdc6 Homologues Is Regulated by DNA [PDF]
Journal of Bacteriology, 2001 ABSTRACTThe initiator protein Cdc6 (Cdc18 in fission yeast) plays an essential role in the initiation of eukaryotic DNA replication. In yeast the protein is expressed before initiation of DNA replication and is thought to be essential for loading of the helicase onto origin DNA.
B, Grabowski, Z, Kelman
openaire +2 more sources