Results 21 to 30 of about 3,017,680 (323)
ATAC-seq identifies thousands of extrachromosomal circular DNA in cancer and cell lines
Science Advances, 2020 EccDNAs are hiding in plain sight in conventional ATAC-seq data. Extrachromosomal circular DNAs (eccDNAs) are somatically mosaic and contribute to intercellular heterogeneity in normal and tumor cells.
Pankaj Kumar +8 more
semanticscholar +1 more source
To Be or Not to Be: Circular RNAs or mRNAs From Circular DNAs? [PDF]
Frontiers in Genetics, 2019 In recent years, there has been a growing interest in circular RNAs (circRNAs) since they are involved in a wide spectrum of cellular functions that might have a large impact on phenotype and disease. CircRNAs are mainly recorded by RNA-Seq and computational methods focused on the detection of back-splicing junction sequences considered the diagnostic ...
Iparraguirre, Leire +3 more
openaire +6 more sources
bioRxiv, 2020 Circular DNA of chromosomal origin form from all parts of eukaryotic genomes. In yeast, circular rDNA accumulates as cells divide, contributing to replicative aging.
I. Prada-Luengo +8 more
semanticscholar +1 more source
Circular DNA's from HeLa cell nuclei and mitochondria [PDF]
, 1970 An electron microscopic observation was made on the DNA's extracted from purified HeLa cell nuclei, mitochondria, and the whole cell, and fractionated by ethidium bromide-cesium chloride density gradient method or sucrose density gradient method. Nuclear
Hirata, Seiichi +4 more
core +1 more source
DNA-like Helices as Nanosized Polarizers of Electromagnetic Waves
Frontiers in Nanotechnology, 2022 The possibility of using a conducting double DNA-like helix as the basis of an electromagnetic wave polarizer, which converts an incident linearly polarized wave into a reflected wave with circular polarization, has been shown. A high-frequency resonance
Igor V. Semchenko +4 more
doaj +1 more source
The adaptive potential of circular DNA accumulation in ageing cells
Current Genetics, 2020 Carefully maintained and precisely inherited chromosomal DNA provides long-term genetic stability, but eukaryotic cells facing environmental challenges can benefit from the accumulation of less stable DNA species.
R. Hull, J. Houseley
semanticscholar +1 more source
Condensation of circular DNA [PDF]
The Journal of Chemical Physics, 2013 A simple model of a circularly closed double-stranded DNA in a poor solvent is considered as an example of a semi-flexible polymer with self-attraction. To find the ground states, the conformational energy is computed as a sum of the bending and torsional elastic components and the effective self-attraction energy.
openaire +4 more sources
Mitochondrial DNA from hamster tumors induced by adenovirus type 12 [PDF]
, 1970 1. Mitochondria isolated from hamster tumors induced by adenovirus type 12 possessed circular DNA fibers. 2. The mean value of the length of the highest frequency group of the circular DNA molecules was 4.92 ±0.38 μ. 3. Catenated dimer DNA molecules
Nishida, Shigeru, Oda, Takuzo
core +1 more source
Characterization of the DNA binding activity of structural protein VP1 from chicken anaemia virus
BMC Veterinary Research, 2018 Background Chicken anaemia virus (CAV) is commonly found in poultry. VP1 is the sole structural protein of CAV, which is the major component responsible for capsid assembly. The CAV virion consists of the VP1 protein and a viral genome. However, there is
Guan-Hua Lai +7 more
doaj +1 more source
International Journal of Molecular Sciences, 2020 Still unresolved is the question of how a lifetime accumulation of somatic gene copy number alterations impact organ functionality and aging and age-related pathologies.
Quratul Ain +4 more
semanticscholar +1 more source