Results 181 to 190 of about 323,377 (241)

Heterogeneity of Intratumoral Microbiota Within the Tumor Microenvironment and Relationship to Tumor Development

open access: yesMed Research, EarlyView.
Mutual shaping of tumor microbiota and TME. Intratumoral microbiota—comprising diverse bacteria, fungi, viruses, and intracellular organisms—play critical and dynamic roles in shaping the tumor microenvironment (TME). Their spatial and compositional diversity contributes to both intratumoral and intertumoral heterogeneity, influencing immune modulation
Zhifei Gao   +9 more
wiley   +1 more source

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar   +4 more
wiley   +1 more source

Advancements in Magnesium Applications, Biocompatible Implants to Nanoparticles in Medicine and Biomedical Innovations

open access: yesMetalMat, EarlyView.
Magnesium (Mg) and its alloys are identified as prospective materials for orthopedic and cardiovascular applications because of their bio‐corrosiveness and ability to stimulate tissue reparative processes. Although compared with traditional metals, Mg is biocompatible; however, it has various problems that stem from its biodegradation nature, for ...
Muhammad Mubeen   +6 more
wiley   +1 more source

Population genomic analyses reveal extensive genomic regions within selective sweeps associated with adaptation and demographic history of a wheat fungal pathogen

open access: yesNew Plant Protection, EarlyView.
Applying population genomics, this study revealed that Pst exhibits slower linkage disequilibrium decay compared to rust fungi with known sexual reproduction, identified extensive hard and soft sweeps linked to Pst adaptation, and demonstrated that crop domestication and breeding programs have significantly influenced pathogen population sizes ...
Yun Xing   +14 more
wiley   +1 more source

A Laboratory-Developed Assay for the Simultaneous Detection of <i>Aspergillus fumigatus</i> and <i>Pneumocystis jirovecii</i> Pulmonary Pathogens. [PDF]

open access: yesJ Fungi (Basel)
Cacaci M   +8 more
europepmc   +1 more source

Occurrence and integrated control of major rice diseases in China

open access: yesNew Plant Protection, EarlyView.
Rice is constantly under threat from a variety of pathogens. This review highlights the major diseases affecting rice in China, including three fungal diseases, two bacterial diseases, two viral diseases, and one nematode. The review also proposes future directions for an integrated approach to control these significant rice diseases.
Ruyi Wang   +13 more
wiley   +1 more source

Effects of boreal ground layer shrubs and bryophytes on the diversity, biomass and composition of lichen communities across contrasting ecosystems

open access: yesOikos, EarlyView.
There has been much recent interest in understanding how abiotic factors such as light, nutrients, and soil moisture affect the composition and biomass of lichen communities. Meanwhile, whether and how ground layer vegetation such as bryophytes and shrubs also influence lichen communities have received much less attention, particularly regarding how ...
Nicolas Fanin   +5 more
wiley   +1 more source

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