Results 11 to 20 of about 3,292,865 (329)

Staphylococcus aureus Protection-Related Type 3 Cell-Mediated Immune Response Elicited by Recombinant Proteins and GM-CSF DNA Vaccine

Vaccines, 2021
Staphylococcus aureus mastitis remains a major challenge for dairy farming. Here, 24 mice were immunized and divided into four groups: G1: control; G2: Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) DNA vaccine; G3: F0F1 ATP synthase subunit α
Kamila R. Santos, Fernando N. Souza, Eduardo M. Ramos-Sanchez, Camila F. Batista, Luiza C. Reis, Wesley F. Fotoran, Marcos B. Heinemann, Hiro Goto, Magnus Gidlund, Adriano F. Cunha, Angélica Rosa Faria, Hélida M. Andrade, Andrey P. Lage, Mônica M. O. P. Cerqueira, Alice M. M. P. Della Libera   +14 more
doaj   +1 more source

Gel-Based Purification and Biochemical Study of Laccase Isozymes from Ganoderma sp. and Its Role in Enhanced Cotton Callogenesis

Frontiers in Microbiology, 2017
Basidiomycetous fungi, Ganoderma lucidum MDU-7 and Ganoderma sp. kk-02 secreted multiple laccase isozymes under diverse growth condition. Aromatic compounds and metal salts were also found to regulate the differential expression of laccase isozymes from ...
Krishna K. Sharma, Amit Kumar, Amit Kumar, Deepti Singh, Sakshi Arora, Amarjeet K. Singh, Sarvajeet S. Gill, Barkha Singhal   +7 more
doaj   +1 more source

Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro [PDF]

, 2010
Initiation of mammalian DNA replication can be reconstituted from isolated G1-phase nuclei and cell extracts, supplemented with cyclin-dependent protein kinases (CDKs).
Ainscough, Berezney, Brown, Cardoso, Chevalier, Cook, Coverley, Coverley, den Hollander, Dijkwel, Djeliova, Fujita, Furstenthal, Geng, Geng, Harper, Hozak, Krude, Lowe, Mailand, Mitsui, Moore, Parisi, Radichev, Sherr, Stoeber, Su, Takeda, Tatsumi, Wilmes, Wohlschlegel   +30 more
core   +3 more sources

Investigating BB0405 as a novel Borrelia afzelii vaccination candidate in Lyme borreliosis

Scientific Reports, 2021
BB0405 is a surface exposed Borrelia burgdorferi protein and its vaccination protected mice against B. burgdorferi infection. As BB0405 is highly conserved across different B.
M. J. Klouwens, J. J. Trentelman, J. I. Ersoz, F. Nieves Marques Porto, R. Sima, O. Hajdusek, M. Thakur, U. Pal, J. W. Hovius   +8 more
doaj   +1 more source

MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA [PDF]

, 2012
Topoisomerase II creates a double-strand break intermediate with topoisomerase covalently coupled to the DNA via a 5'-phosphotyrosyl bond. These intermediate complexes can become cytotoxic protein-DNA adducts and DSB repair at these lesions requires ...
Austin, Caroline, Cockell, Simon, Cowell, Ian, Curtis, Hannah, Jackson, Graham, Lee, Ka Cheong, Moiani, Davide, Morris, Nicholas, Padget, Kay, Sondka, Zbyslaw, Tainer, John   +10 more
core   +3 more sources

Cloning of cDNA Encoding GRA1 Protein of Tachyzoite Toxoplasma Gondii Local Isolate

Indonesian Journal of Biotechnology, 2005
Gene encoding GRA1 protein is potent DNA-vaccine candidate against toxoplasmosis. The aim of the research was to clone the gene encoding GRA1 protein of tachyzoite Toxoplasma gondii local isolate by DNA recombinant technology.
Erma Sulistyaningsih, Sukarti Moeljopawiro, Jarot Subandono, Wayan T. Artama   +3 more
doaj   +1 more source

Cloning and expression of codon-optimized recombinant darbepoetin alfa in Leishmania tarentolae T7-TR [PDF]

, 2016
Darbepoetin alfa is an engineered and hyperglycosylated analog of recombinant human erythropoietin (EPO) which is used as a drug in treating anemia in patients with chronic kidney failure and cancer.
Fard-Esfahani, P., Golavar, R., Khajeniazi, S., Kianmehr, A., Mahrooz, A., Mostafavi, S.S., Oladnabi, M., Omidinia, E., Rouintan, M.   +8 more
core   +1 more source

Recent Developments in Bioprocessing of Recombinant Proteins: Expression Hosts and Process Development

Frontiers in Bioengineering and Biotechnology, 2019
Infectious diseases, along with cancers, are among the main causes of death among humans worldwide. The production of therapeutic proteins for treating diseases at large scale for millions of individuals is one of the essential needs of mankind.
N. Tripathi, A. Shrivastava
semanticscholar   +1 more source

The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM [PDF]

, 2009
The activation of ATR-ATRIP in response to double-stranded DNA breaks (DSBs) depends upon ATM in human cells and Xenopus egg extracts. One important aspect of this dependency involves regulation of TopBP1 by ATM.
Abraham R. T., Akiko Kumagai, Andrej Shevchenko, Anna Shevchenko, Bakkenist C. J., Byun T. S., Caldecott K. W., Chapman J. R., Cimprich K. A., Cortez D., Costanzo V., Costanzo V., Cuadrado M., Daniel J. Lew, Delacroix S., Garcia V., Glover J. N., Goldberg M., Guo Z., Hae Yong Yoo, Hashimoto Y., Jazayeri A., Kobayashi T., Kumagai A., Kumagai A., Kumagai A., Kumagai A., Lee J., Lee J. H., Liu Q., Melander F., Mordes D. A., Morishima K., Myers J. S., Nyberg K. A., Parrilla-Castellar E. R., Perry J. A., Qin X. F., Rupnik A., Sancar A., Shevchenko A., Shiloh Y., Spycher C., Stewart G. S., Walter J., Waridel P., William G. Dunphy, Williams R. S., Wu L., Yoo H. Y., Yoo H. Y., Yoo H. Y., Yoo H. Y., You Z., You Z., Zhao H., Zou L.   +56 more
core   +2 more sources

Recombinant DNA production of spider silk proteins

Microbial Biotechnology, 2013
Spider dragline silk is considered to be the toughest biopolymer on Earth due to an extraordinary combination of strength and elasticity. Moreover, silks are biocompatible and biodegradable protein‐based materials.
Olena S Tokareva, V. Michalczechen-Lacerda, E. Rech, D. Kaplan   +3 more
semanticscholar   +1 more source