Results 371 to 380 of about 662,270 (393)
Some of the next articles are maybe not open access.
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.
Science, 1988A thermostable DNA polymerase was used in an in vitro DNA amplification procedure, the polymerase chain reaction. The enzyme, isolated from Thermus aquaticus, greatly simplifies the procedure and, by enabling the amplification reaction to be performed at
R. Saiki +7 more
semanticscholar +1 more source
Effect of granaticin on the activity of DNA-directed RNA polymerase fromStreptomyces granaticolor
Folia Microbiologica, 1989DNA-directed RNA polymerase was isolated from wild-type and mutant (asporogenic and granaticin overproducing) Streptomyces granaticolor. The effect of granaticin on the enzyme activity was compared with that of standard transcription inhibitors, rifampicin and rifamycin SV and shown to be zero.
Spízek J +3 more
openaire +2 more sources
DNA-directed RNA polymerase from HeLa cells
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1975Abstract DNA-directed RNA polymerase was solubilized from total HeLa cells. Three distinct classes of the enzyme could be clearly differentiated by their sensitivity toward α-amanitin. While form A is completely resistant to high concentrations (133 μg/ml) of this toxin, enzyme B is highly sensitive and is completely inhibited by concentrations of 0 ...
Bernd J. Benecke, Klaus H. Seifart
openaire +2 more sources
Environmental Toxicology and Pharmacology, 2012
The aryl hydrocarbon receptor (AhR) mediates a variety of biological responses to ubiquitous environmental pollutants. AhR is ligand activated transcription factor with high affinities for aromatic planar compounds such as β-naphthoflavone (BNF), 3-methylcholanthrene (3-MC), benzo[a]pyrene (BaP) or dioxin (TCDD).
Agnieszka Anna Rawłuszko, Damian Brauze
openaire +3 more sources
The aryl hydrocarbon receptor (AhR) mediates a variety of biological responses to ubiquitous environmental pollutants. AhR is ligand activated transcription factor with high affinities for aromatic planar compounds such as β-naphthoflavone (BNF), 3-methylcholanthrene (3-MC), benzo[a]pyrene (BaP) or dioxin (TCDD).
Agnieszka Anna Rawłuszko, Damian Brauze
openaire +3 more sources
The isolation and properties of a DNA-directed RNA polymerase from yeast mitochondria
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976A method is described for the rapid isolation of yeast mitochondrial DNA-directed RNA polymerase. The enzyme obtained had a specific activity of 1.56 nmol UMP incorporated per mg protein in 20 min at 37 degrees C, and is some 95% pure. This purified enzyme upon polyacrylamide gel elctrophoresis consists of a single polypeptide of 68 000 mol.
openaire +3 more sources
Mitochondrial DNA-directed RNA polymerase from Saccharomyces cerevisae mitochondria
Biochemical and Biophysical Research Communications, 1971Abstract A DNA-directed RNA polymerase activity has been detected in yeast mitochondrial extracts which is sensitive to rifampicin. This activity is distinct from that found in the nucleus and cytoplasm, and is possibly coded for, or under the control of the mitochondrial genome.
openaire +3 more sources
Journal of Cancer Research and Clinical Oncology, 2023
DNA-directed RNA polymerase (DDRP) related genes and long non-coding RNAs (lncRNAs) play an important role in the development of lung adenocarcinoma (LUAD), the leading cause of cancer-related death worldwide. Therefore, we aimed to construct a DDRP-associated lncRNA model to predict the prognosis of LUAD and to evaluate its sensitivity to ...
Jiaao, Yu +3 more
openaire +2 more sources
DNA-directed RNA polymerase (DDRP) related genes and long non-coding RNAs (lncRNAs) play an important role in the development of lung adenocarcinoma (LUAD), the leading cause of cancer-related death worldwide. Therefore, we aimed to construct a DDRP-associated lncRNA model to predict the prognosis of LUAD and to evaluate its sensitivity to ...
Jiaao, Yu +3 more
openaire +2 more sources
Journal of Proteome Research, 2014
Enzymatic machineries fundamental for information processing (e.g., transcription, replication, translation) in Archaea are simplified versions of their eukaryotic counterparts. This is clearly noticeable in the conservation of sequence and structure of corresponding enzymes (see for example the archaeal DNA-directed RNA polymerase (RNAP)). In Eukarya,
Mikel Azkargorta +3 more
openaire +3 more sources
Enzymatic machineries fundamental for information processing (e.g., transcription, replication, translation) in Archaea are simplified versions of their eukaryotic counterparts. This is clearly noticeable in the conservation of sequence and structure of corresponding enzymes (see for example the archaeal DNA-directed RNA polymerase (RNAP)). In Eukarya,
Mikel Azkargorta +3 more
openaire +3 more sources
Analysis of a baculovirus gene presenting homologies with some DNA directed RNA polymerases.
1994International ...
Durantel, D., Lopez-Ferber, Miguel
openaire +2 more sources
RNA-directed DNA polymerase--properties and functions in oncogenic RNA viruses and cells.
Progress in Nucleic Acid Research and Molecular Biology, 1974M. Green, Gary F. Gerard
semanticscholar +1 more source