DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts. [PDF]
Alkylating agents, such as methyl methanesulfonate (MMS), damage DNA and activate the DNA damage checkpoint. Although many of the checkpoint proteins that transduce damage signals have been identified and characterized, the mechanism that senses the ...
Lindsay, Howard D. +11 more
core +5 more sources
Electronic transport in DNA [PDF]
We study the electronic properties of DNA by way of a tight-binding model applied to four particular DNA sequences. The charge transfer properties are presented in terms of localization lengths (crudely speaking, the length over which electrons travel).
Klotsa, Daphne +3 more
core +1 more source
Genotoxikus hatásra bekövetkező funkcionális és strukturális DNS változások = Functional and structural changes in DNA upon genotoxic effects [PDF]
Morfológiai és biokémiai vizsgálataink arra utalnak, hogy a a genotoxikus hatások kategorizálhatók az okozott kromatin változások alapján. A kemotoxikus változások potenciális diagnosztikus jelentősége miatt vizsgáltuk a nehézfémek (elsősosrban kadmium) (
Szepessy, Edit +6 more
core +1 more source
This study introduces new model of digital repositories called Trusted Third Party Repository (TTPR) in Korea, its service offerings and business impacts.
Cho, Namdo
core +1 more source
Molecular mechanisms and kinetics between DNA and DNA binding ligands [PDF]
Sischka A, Tönsing K, Eckel R, et al. Molecular mechanisms and kinetics between DNA and DNA binding ligands. Biophysical Journal. 2005;88(1):404-411.Mechanical properties of single double-stranded DNA (dsDNA) in the presence of different binding ligands ...
Anselmetti, Dario +9 more
core +1 more source
Cellular Processing Pathways Contribute to the Activation of Etoposide- Induced DNA Damage Responses
Cytotoxic action (tumor cell killing) and carcinogenic side effect ( therapy-related secondary leukemia) of etoposide are closely related to its ability in stabilizing topoisomerase II cleavable complex (TOP2cc), a unique form of protein- linked DNA ...
FAN, JIA-RONG;PENG, AN-LIN;LO, SHU-CHI;HUANG, TING-HSIANG;LI, TSAI-KUN +1 more
core +1 more source
Peranan dan fungsi Tribunal Tuntutan Pembeli Rumah (TTPR) dalam industri hartanah di Malaysia / Mohd Azanizam Samsudin [PDF]
Tribunal Tuntutan Pembeli Rumah (TTPR) ditubuhkan bagi memberi perlindungan kepada pembeli rumah dan mempercepatkan tuntutan daripada pembeli rumah. Tribunal ini juga dapat mengurangkan karenah birokrasi dan tidak memerlukan peguam serta keputusan yang ...
Samsudin, Mohd Azanizam
core
Maternal nutritional status, C1 metabolism and offspring DNA methylation: a review of current evidence in human subjects. [PDF]
: Evidence is growing for the long-term effects of environmental factors during early-life on later disease susceptibility. It is believed that epigenetic mechanisms (changes in gene function not mediated by DNA sequence alteration), particularly DNA ...
Dominguez Salas, Paula +19 more
core +1 more source
A DNA vaccine construct incorporating intercellular trafficking and intracellular targeting motifs effectively primes and induces memory B and T cell responses in outbred animals [PDF]
We developed a vaccine construct in which a BVP22 domain and an invariant-chain major histocompatibility complex class II-targeting motif capable of enhancing dendritic cell antigen uptake and presentation were fused to a sequence encoding a B- and T ...
Palmer, Guy H +19 more
core +1 more source
In the present thesis, the induction and repair of complex DNA lesions, double strand breaks (DSBs) of high complexity accompanied by oxidatively-induced base lesions in their close vicinity were studied after exposure to ionizing radiation (IR) of ...
Νικητάκη, Ζαχαρένια +2 more
core +1 more source

