Results 351 to 360 of about 7,795,985 (403)

Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β. [PDF]

Nat Commun
Weaver TM, Ryan BJ, Thompson SH, Hussen AS, Spencer JJ, Xu Z, Schnicker NJ, Freudenthal BD.   +7 more
europepmc   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Density and structure of DNA immobilised on gold nanoparticles affect sensitivity in nucleic acid detection. [PDF]

Sci Rep
Fukuzumi N, Hirao G, Ogawa A, Asahi T, Maeda M, Zako T.   +5 more
europepmc   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

P845: HemaSure-OMXP: A non-toxic venous whole blood collection device enabling the 14-day room temperature stabilization of cell-free DNA

Genetics in Medicine Open
Andrew Wood, Veronika Rapoport, Ying Wang   +2 more
doaj  

Contrasting effects of mismatch locations on Z-DNA formation under bending force. [PDF]

Chem Sci
Park S, Yi J, Lee NK.
europepmc   +1 more source

Visualization of protrusion-localized STAT3 mRNA using a self-powered lipidic nanoflare for predicting hepatocellular carcinoma metastasis. [PDF]

Mikrochim Acta
Zhang Y, Zeng R, Xia Y, Han W, Luan Y, Zhang Y, Wu S, Wang S, Wang J, Chen Y, Chen D.   +10 more
europepmc   +1 more source

The role of water in mediating DNA structures with epigenetic modifications, higher-order conformations and drug-DNA interactions. [PDF]

RSC Chem Biol
Satange R, Hou MH.
europepmc   +1 more source

Ligase-catalyzed transcription and reverse-transcription of XNA-containing nucleic acid polymers using T3 DNA ligase. [PDF]

Chem Sci
Khamissi N, Korfmann C, Chaudhry A, Hili R.   +3 more
europepmc   +1 more source