Results 221 to 230 of about 40,057 (283)
Site‐Selective Ligand Selection by Mutational Profiling for Covalent RNA Targeting
Using a mutational profiling approach an RNA‐targeted covalent probe was developed that is highly selective for the FMN riboswitch. The covalency was further supported by mass spectrometry experiments. The covalent probe selectively modifies the riboswitch at low micromolar concentrations within 10 min and remains functional when applied to an entire ...
Phillip Yesley +3 more
wiley +2 more sources
Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy
Cerebral palsy, caused by non‐progressive brain injury, is frequently accompanied by skeletal muscle alterations. This review synthesizes current evidence from muscle biopsy studies, revealing cellular and molecular adaptations in muscle tissue. Abstract Cerebral palsy (CP), the most prevalent childhood‐onset motor disability, frequently entails ...
Sebastian Edman +4 more
wiley +1 more source
Paclitaxel Enhances Carboplatin-DNA Adduct Formation and Cytotoxicity. [PDF]
Jiang S +7 more
europepmc +1 more source
The role of cytokines in ovarian cancer drug resistance
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang +7 more
wiley +1 more source
Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan +3 more
wiley +2 more sources
What's new? This study quantified the cancer burden attributable to modifiable risk factors in Guangdong, the most populous and economically advanced province in southern China. By evaluating 15 modifiable risk factors, the study reveals that over one‐third of cancer cases and two‐fifths of cancer deaths in the region could potentially be prevented ...
Xiaolan Wen +17 more
wiley +1 more source
Benzo(a)pyrene Diolepoxide-DNA Adducts Detected by Synchronous Fluorescence Spectrophotometry
Kirsi Vähäkangas +3 more
openalex +1 more source

