Formation and properties of endogenous adducts and crosslinks generated by amine-catalyzed strand cleavage at an AP site in duplex DNA [PDF]
, 2022 Jay S. Jha
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Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo
Chemistry – A European Journal, EarlyView.This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova +2 more
wiley +1 more source
Novel mechanisms for the removal of strong replication-blocking HMCES- and thiazolidine-DNA adducts in humans. [PDF]
Nucleic Acids Res, 2023 Sugimoto Y +5 more
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Rational Design Strategies for Stimuli‐Responsive DNAzymes Using Modified and Artificial Nucleotides
Chemistry – A European Journal, EarlyView.Activity control of RNA‐cleaving DNAzymes in response to external stimuli has attracted growing interest for applications in DNA‐based diagnostics, therapeutics, and dynamic DNA nanotechnology. This review summarizes rational design strategies for stimuli‐responsive DNAzymes using modified or artificial nucleotides, including split and caged DNAzymes ...
Yusuke Takezawa, Mitsuhiko Shionoya
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ChemMedChem, EarlyView.Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto +12 more
wiley +1 more source
Increased acrolein-DNA adducts in buccal brushings of e-cigarette users. [PDF]
Carcinogenesis, 2022 Cheng G +9 more
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Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis
Clinical Pharmacology &Therapeutics, EarlyView.Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic +4 more
wiley +1 more source
Aflatoxin B1-DNA adducts modify the effects of post-operative adjuvant transarterial chemoembolization improving hepatocellular carcinoma prognosis. [PDF]
Explor Target Antitumor Ther, 2023 Huang L, Long Q, Su Q, Zhu X, Long X.
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Lipid peroxidation-induced DNA adducts in human gastric mucosa [PDF]
, 2012 Tomonari Matsuda +17 more
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Myomaker and Myomixer are required for craniofacial myoblast fusion in zebrafish
Developmental Dynamics, EarlyView.Abstract Background Craniofacial and trunk skeletal muscles are derived from different progenitor populations during development. Trunk skeletal muscles contain mostly multinucleated myofibers that are formed through myoblast fusion. However, myoblast fusion in craniofacial muscles and its molecular regulation are not well understood.
Zhanxiong Zhang +3 more
wiley +1 more source