Results 121 to 130 of about 2,170,594 (309)

Self-assembling DNA-caged particles: nanoblocks for hierarchical self-assembly [PDF]

open access: yes, 2008
DNA is an ideal candidate to organize matter on the nanoscale, primarily due to the specificity and complexity of DNA based interactions. Recent advances in this direction include the self-assembly of colloidal crystals using DNA grafted particles. In this article we theoretically study the self-assembly of DNA-caged particles. These nanoblocks combine
arxiv   +1 more source

Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts

open access: yesNucleic Acids Research, 2011
Exposure to aristolochic acid (AA), a component of Aristolochia plants used in herbal remedies, is associated with chronic kidney disease and urothelial carcinomas of the upper urinary tract.
V. Sidorenko   +5 more
semanticscholar   +1 more source

Unexpected transformation of dissolved phenols to toxic dicarbonyls by hydroxyl radicals and UV light. [PDF]

open access: yes, 2018
Water treatment systems frequently use strong oxidants or UV light to degrade chemicals that pose human health risks. Unfortunately, these treatments can result in the unintended transformation of organic contaminants into toxic products.
Ford, Breanna   +3 more
core   +1 more source

Smoking, DNA Adducts and Number of Risk DNA Repair Alleles in Lung Cancer Cases, in Subjects with Benign Lung Diseases and in Controls

open access: yesJournal of Nucleic Acids, 2010
Smoke constituents can induce DNA adducts that cause mutations and lead to lung cancer. We have analyzed DNA adducts and polymorphisms in two DNA repair genes, for example, XRCC1 Arg194Trp and Arg399Gln genes and XRCC3 Thr241Met gene, in 34 lung cancer ...
Marco Peluso   +6 more
doaj   +1 more source

Capacity of DNA Data Embedding Under Substitution Mutations [PDF]

open access: yes, 2011
A number of methods have been proposed over the last decade for encoding information using deoxyribonucleic acid (DNA), giving rise to the emerging area of DNA data embedding. Since a DNA sequence is conceptually equivalent to a sequence of quaternary symbols (bases), DNA data embedding (diversely called DNA watermarking or DNA steganography) can be ...
arxiv   +1 more source

Distribution of DNA adducts caused by inhaled formaldehyde is consistent with induction of nasal carcinoma but not leukemia.

open access: yesToxicological Sciences, 2010
Inhaled formaldehyde is classified as a known human and animal carcinogen, causing nasopharyngeal cancer. Additionally, limited epidemiological evidence for leukemia in humans is available; however, this is inconsistent across studies.
Kun Lu   +4 more
semanticscholar   +1 more source

Adaptive Response Enzyme AlkB Preferentially Repairs 1-Methylguanine and 3-Methylthymine Adducts in Double-Stranded DNA [PDF]

open access: yes, 2018
The AlkB protein is a repair enzyme that uses an α-ketoglutarate/Fe(II)-dependent mechanism to repair alkyl DNA adducts. AlkB has been reported to repair highly susceptible substrates, such as 1-methyladenine and 3-methylcytosine, more efficiently in ss ...
Bian, Ke   +8 more
core   +1 more source

DNA Adducts with Lipid Peroxidation Products [PDF]

open access: yesJournal of Biological Chemistry, 2008
Homolytic decomposition of PUFA2-derived lipid hydroperoxides results in formation of the α,β-unsaturated aldehydic bifunctional electrophiles DDE, EDE, HNE, HPNE, MDA (shown as β-hydroxyacrolein), ONE, DODE, and 5,8-dioxo-(10E)-octenoic acid (see Fig. 1) (1–3).
openaire   +3 more sources

Formation of DNA Adducts by Ellipticine and Its Micellar Form in Rats — A Comparative Study

open access: yesSensors, 2014
The requirements for early diagnostics as well as effective treatment of cancer diseases have increased the pressure on development of efficient methods for targeted drug delivery as well as imaging of the treatment success.
Marie Stiborova   +5 more
doaj   +1 more source

Study on the Electronic Structure and Stability of Some Endohedral Fullerenes - RE3N@C80 (RE = Sc, Y, La) by PM7 [PDF]

open access: yesarXiv, 2014
In this paper, we investigated the electronic structure of some endohedral fullerenes containing rare earth nitride and the stability of their benzyne-adducts by PM7, the semiempirical Hatree-Fock method.
arxiv  

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