Results 101 to 110 of about 34,648 (287)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

DNA Barcode Sequence Identification Incorporating Taxonomic Hierarchy and within Taxon Variability

PLoS ONE, 2011
For DNA barcoding to succeed as a scientific endeavor an accurate and expeditious query sequence identification method is needed. Although a global multiple-sequence alignment can be generated for some barcoding markers (e.g. COI, rbcL), not all barcoding markers are as structurally conserved (e.g. matK). Thus, algorithms that depend on global multiple-
openaire   +3 more sources

Combining and Comparing Coalescent, Distance and Character-Based Approaches for Barcoding Microalgaes: A Test with Chlorella-Like Species (Chlorophyta). [PDF]

PLoS ONE, 2016
Several different barcoding methods of distinguishing species have been advanced, but which method is the best is still controversial. Chlorella is becoming particularly promising in the development of second-generation biofuels. However, the taxonomy of
Shanmei Zou, Cong Fei, Jiameng Song, Yachao Bao, Meilin He, Changhai Wang   +5 more
doaj   +1 more source

The CCAP KnowledgeBase : linking protistan and cyanobacterial biological resources with taxonomic and molecular data [PDF]

, 2013
Peer ...
Achilles-Day, Undine E M, Blaxter, Mark, Brennan, Debra, Campbell, Christine N, Clarke, Alison, Day, John G, Dorrell, Richard G, Field, Joanne, Gachon, Claire M M, Gharbi, Karim, Gontarek, Steven, Guiry, Michael D, Heesch, Svenja, Kuepper, Frithjof C, Menendez, Cecilia Rad, Saxon, Rachel J, Veszelovszki, Andrea   +16 more
core   +2 more sources

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

Advanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo, Ewa Anna Oprzeska‐Zingrebe, Mariana Kozlowska, Lennart Hilbert, Iliya D. Stoev   +4 more
wiley   +1 more source

Using taxonomic consistency with semi‐automated data pre‐processing for high quality DNA barcodes [PDF]

Methods in Ecology and Evolution, 2017
Abstract In recent years, large‐scale DNA barcoding campaigns have generated an enormous amount of COI barcodes, which are usually stored in NCBI's GenBank and the official Barcode of Life database (BOLD). BOLD data are generally associated with more detailed and better curated meta‐data, because a great proportion is based on expert‐verified and ...
Björn Rulik, Jonas Eberle, Laura von der Mark, Jana Thormann, Manfred Jung, Frank Köhler, Wolfgang Apfel, Andreas Weigel, Andreas Kopetz, Jonas Köhler, Frank Fritzlar, Matthias Hartmann, Karl Hadulla, Joachim Schmidt, Thomas Hörren, Detlef Krebs, Florian Theves, Ute Eulitz, André Skale, Dirk Rohwedder, Andreas Kleeberg, Jonas J. Astrin, Matthias F. Geiger, J. Wolfgang Wägele, Peter Grobe, Dirk Ahrens   +25 more
openaire   +2 more sources

Comparative Study of DNA Barcoding and Mini-Barcoding based on COI Gene for Species Identification and Phylogeny of Formicidae Family (Insecta: Hymenoptera)

Hayati Journal of Biosciences
DNA barcoding and mini-barcoding are widely used to study insect biodiversity, including ants (Hymenoptera: Formicidae). This study evaluated the effectiveness of both approaches for species identification and phylogenetic inference in ants, with ...
Beivy Jonathan Kolondam, Trina Ekawati Tallei, Roni Koneri, Juliet Merry Eva Mamahit   +3 more
doaj   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

DNA barcodes from four loci provide poor resolution of taxonomic groups in the genus Crataegus [PDF]

AoB PLANTS, 2015
DNA barcodes can facilitate identification of organisms especially when morphological characters are limited or unobservable. To what extent this potential is realized in specific groups of plants remains to be determined. Libraries of barcode sequences from well-studied authoritatively identified plants represented by herbarium voucher specimens are ...
Zarrei, Mehdi, Talent, Nadia, Kuzmina, Maria, Lee, Jeanette, Lund, Jensen, Shipley, Paul R., Stefanović, Saša, Dickinson, Timothy A.   +7 more
openaire   +2 more sources

DNA barcodes from snake venom: a broadly applicable method for extraction of DNA from snake venoms

BioTechniques, 2018
DNA barcoding is a simple technique used to develop a large-scale system of classification that is broadly applicable across a wide variety of taxa.
Cara Francesca Smith, Mitchell E McGlaughlin, Stephen P Mackessy   +2 more
doaj   +1 more source