Results 91 to 100 of about 328,318 (240)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

DNA StairLoop: enabling high-fidelity data recovery and robust error correction in DNA-based data storage

Nature Communications
High-throughput electrochemical synthesis is an emerging DNA synthesis technology that has attracted considerable attention due to its scalability and cost-effectiveness.
Zihui Yan, Guanjin Qu, Xin Chen, Gang Zheng, Huaming Wu   +4 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

RETRACTED: Bionic‐structure thermo‐responsive (best) hydrogels with controllable layer for high‐capacity DNA data storage

Nano Select
Here, a new‐rising technology (DNA storage) in which the binary digital information/data is converted into a DNA sequence composed of distinct nucleotides, providing a dense, stable, energy‐efficient, and sustainable data storage solution is studied.
Zhongjie Fei, Mengjie Li, Chu Cheng, Guolei Tan, Pengfeng Xiao   +4 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Advancing Efficient Error Reduction in DNA Data Storage Systems with Deep Learning‐Based Denoising Models

Advanced Intelligent Discovery
DNA data storage systems have made significant strides toward addressing the limitations of traditional storage media. Research in this field emphasizes innovative approaches that leverage the biochemical properties of DNA for high‐density and efficient ...
Seongjun Seo, Anshula Tandon, Nguyen Kim Uyen, Quoc Nam Le, Jee‐Hyong Lee, Sung Ha Park   +5 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Neural Polar Decoders for DNA Data Storage

IEEE Journal on Selected Areas in Information Theory
Synchronization errors, such as insertions and deletions, present a fundamental challenge in DNA-based data storage systems, arising from both synthesis and sequencing noise. These channels are often modeled as insertion-deletion-substitution (IDS) channels, for which designing maximum-likelihood decoders is computationally expensive.
Ziv Aharoni, Henry D. Pfister
openaire   +4 more sources

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Unlocking the Future for the New Data Paradigm of DNA Data Storage : An Investigative Analysis of Advancements, Challenges, Future Directions

Journal of Information Sciences
This research dives into the potential of DNA as a revolutionary data storage solution for the ever-growing digital age. It explores how recent advancements in synthetic biology and unconventional computing methods can be leveraged to create robust and ...
Zarif Bin AKHTAR, Ahmed TAJBIUL RAWOL
doaj   +1 more source