Repair of oxidatively induced DNA damage by DNA glycosylases: Mechanisms of action, substrate specificities and excision kinetics. [PDF]
Dizdaroglu M, Coskun E, Jaruga P.
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Hide and seek: How do DNA glycosylases locate oxidatively damaged DNA bases amidst a sea of undamaged bases? [PDF]
Lee AJ, Wallace SS.
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Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation. [PDF]
Schomacher L+6 more
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Mutant E.Coli 3-methyladenine DNA glycosylase II reveals AP-lyase activity
Hironobu Nakano+4 more
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Repair pathway coordination from gap filling by polβ and subsequent nick sealing by LIG1 or LIG3α governs BER efficiency at the downstream steps. [PDF]
Çağlayan M.
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Inhibition by 4-(4-Bromo-2-oxo-3<i>H</i>-benzimidazol-1-yl)-<i>N</i>-(4-iodophenyl)piperidine-1-carboxamide (TH5487) of the Activity of Human 8-Oxoguanine DNA Glycosylase-1 (OGG1) for the Excision of 2,6-Diamino-4-hydroxy-5-formamidopyrimidine, 4,6-Diamino-5-formamidopyrimidine, and 8-Oxoguanine from Oxidatively Damaged DNA. [PDF]
Jaruga P+5 more
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Decoding mitochondrial DNA damage and repair associated with <i>H. pylori</i> infection. [PDF]
Shahi A, Kidane D.
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Various DNA glycosylases exist, which initiate the first step in base-excision repair. A summary of the kinetic and physical characteristics of three classes of DNA glycosylases are presented here. The first class discussed, include glycosylases which recognize alkylated DNA.
S J, Caradonna, Y C, Cheng
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A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase
Nature, 1996Mispairs in DNA of guanine with uracil and thymine can arise as a result of deamination of cytosine and 5-methylcytosine, respectively. In humans such mispairs are removed by thymine-DNA glycosylase (TDG). By deleting the carboxy and amino termini of this enzyme we have identified a core region capable of processing G/U but not G/T mispairs.
Gallinari, P, Jiricny, J
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