BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Discovery and technical validation of high-performance methylated DNA markers for the detection of cervical lesions at risk of malignant progression in low- and middle-income countries. [PDF]
Clin EpigeneticsFackler MJ +18 more
europepmc +1 more source
Are There Barriers Separating the Pink River Dolphin Populations (Inia boliviensis, Iniidae, Cetacea) within the Mamoré-Iténez River Basins (Bolivia)? An Analysis of Its Genetic Structure by Means of Mitochondrial and Nuclear DNA Markers. [PDF]
Genes (Basel)Ruiz-García M +6 more
europepmc +1 more source
Correction to "Protein Coding Low-Copy <i>rpb2</i> and <i>ef1-α</i> Regions Are Viable Fungal Metabarcoding DNA Markers Which Can Supplement ITS for Better Accuracy". [PDF]
Ecol Evoleuropepmc +1 more source
An accurate diagnostic approach for urothelial carcinomas based on novel dual methylated DNA markers in small-volume urine. [PDF]
Chin Med J (Engl)Wu Y +17 more
europepmc +1 more source
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Given a genome, i.e., a long string over a fixed finite alphabet, the problem is to find short (dis)similar substrings. This computationally intensive task has many biological applications. We first describe an algorithm to detect substrings that have edit distances to a fixed substring at most equal to a given.
Hendrik Jan Hoogeboom +2 more
openaire +2 more sources
Chromosome Mapping with DNA Markers
Scientific American, 1988New markers called RFLP's (for restriction-fragment length polymorphisms) can indicate the location on a chromosome of a disease-causing gene and serve to identify carriers. With enough markers one can map the human chromosomes--the first step toward an ambitious goal of molecular biology: sequencing the entire human genome.
R, White, J M, Lalouel
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A Marker for Mammalian DNA Sedimentation
Radiation Research, 1974DNA from Chinese hamster ovary (CHO) cells which had been irradiated with 1 krad of x rays was sedimented in alkaline sucrose gradients with the single strands of DNA and large DNA-containing species which can be released from mammalian cells. It was found that the CHO DNA profile is suited for use as a marker in such circumstances because it has both ...
K T, Wheeler, J, DeWitt, J T, Lett
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DNA markers in forensic medicine
Transfusion Clinique et Biologique, 1995After a description of the various DNA polymorphisms which can be used in forensic medicine, the use of these markers for solving cases of disputed paternity is discussed in detail. VNTR polymorphisms detectable after amplification of the relevant loci by the PCR seem to be the best tools for paternity testing.
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Microsatellites as DNA markers in Sitka spruce
TAG Theoretical and Applied Genetics, 1996Nine microsatellite loci were found by screening a genomic DNA library of Sitka spruce (Picea sitchensis) with the four oligonucleotide probes (TG), (CAC), (GATA) and (AT). Pairs of flanking primers were generated for seven microsatellites. Five primer pairs were used to screen up to 58 Sitka spruce clones.
W T, van de Ven, R J, McNicol
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