Results 151 to 160 of about 2,560,073 (378)

Detection of Human Herpesviruses in Sera and Saliva of Asymptomatic HIV-Infected Individuals Using Multiplex RT-PCR DNA Microarray. [PDF]

open access: yesPathogens, 2023
Sufiawati I   +6 more
europepmc   +1 more source

Analysis of DNA Microarrays by Non-Destructive Fluorescent Staining Using SYBR ® Green II [PDF]

open access: gold, 2000
Cristina Battaglia   +4 more
openalex   +1 more source

The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

open access: yesAdvanced Science, EarlyView.
Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li   +9 more
wiley   +1 more source

DNA microarray technology in medical diagnostics

open access: yesZdravniški Vestnik, 2007
Background: DNA microarray technology opened a completely new venue in the biomedical research. By allowing to follow the expression of thousands of genes in a single experiment (ideally we can follow the expression of the entire genome), the microarray ...
Damjana Rozman, Peter Juvan
doaj  

Examining the Living Genome in Health and Disease With DNA Microarrays [PDF]

open access: bronze, 2000
Maximilian Diehn   +2 more
openalex   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

open access: yesAdvanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro   +10 more
wiley   +1 more source

Osteoblast‐CD4+ CTL Crosstalk Mediated by SIRT1/DAAM2 Axis Prevents Age‐Related Bone Loss

open access: yesAdvanced Science, EarlyView.
In the osteoblastic niche, SIRT1 activates and recruits CD4+ CTLs by increasing DAAM2 expression via EZH2 deacetylation and boosting the secretion of key chemokines, such as CCL3, CCL5, and CXCL10. Then, CD4+ CTL directly eliminates senescent osteoblasts in an MHC‐II‐dependent way, thereby slowing down the process of bone ageing and effectively ...
Bin Yang   +20 more
wiley   +1 more source

Multi‐readout thermoplasmonic biosensor for rapid detection of oligonucleotides

open access: yesView
Developing user‐friendly, high‐performance sensing devices for nucleic acid detection is crucial for diagnostics, drug development, and personalized therapies.
Maria Laura Sforza   +5 more
doaj   +1 more source

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