Results 161 to 170 of about 2,576,927 (378)

The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

Advanced Science, EarlyView.
Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li, Xinrui Li, Yuhui Du, Sijie Chen, Xiaoniu He, Zhangrong Xie, Zhiqing Zhou, Huijie Zhao, Xiaofei Zeng, Guoan Chen   +9 more
wiley   +1 more source

Multi‐readout thermoplasmonic biosensor for rapid detection of oligonucleotides

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Developing user‐friendly, high‐performance sensing devices for nucleic acid detection is crucial for diagnostics, drug development, and personalized therapies.
Maria Laura Sforza, Elisabetta De Marinis, Annalisa Masi, Clara Nervi, Luciano De Sio, Francesca Petronella   +5 more
doaj   +1 more source

Simultaneous Detection of Mycobacterium tuberculosis and Atypical Mycobacteria by DNA-Microarray in Egypt. [PDF]

Med Princ Pract, 2022
Gaballah A, Ghazal A, Almiry R, Emad R, Sadek N, Abdel Rahman M, El-Sherbini E.   +6 more
europepmc   +1 more source

Identification of the Copper Regulon in Saccharomyces cerevisiae by DNA Microarrays [PDF]

, 2000
Claudia Groß, Mark Kelleher, Vishwanath R. Iyer, Patrick O. Brown, Dennis R. Winge   +4 more
openalex   +1 more source

Genome-wide analysis of growth phase-dependent translational and transcriptional regulation in halophilic archaea : research article [PDF]

, 2007
Background Differential expression of genes can be regulated on many different levels. Most global studies of gene regulation concentrate on transcript level regulation, and very few global analyses of differential translational efficiencies exist.
Hammelmann, Mathias, Lange, Christian, Oesterhelt, Dieter, Raddatz, Günter, Schuster, Stephan C., Soppa, Jörg (Prof. Dr.), Twellmeyer, Jens, Zaigler, Alexander   +7 more
core  

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Comparative Study of Classification Algorithms for Various DNA Microarray Data. [PDF]

Genes (Basel), 2022
Kim J, Yoon Y, Park HJ, Kim YH.
europepmc   +1 more source

Analysis of topoisomerase function in bacterial replication fork movement: Use of DNA microarrays [PDF]

, 2000
Arkady Khodursky, Brian J. Peter, Molly B. Schmid, Joseph L. DeRisi, David Botstein, Patrick O. Brown, Nicholas R. Cozzarelli   +6 more
openalex   +1 more source

Deacetylation of ACLY Mediates RNA M6A‐Modification of NOXA and Promotes Chemoresistance of Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the deacetylation of ACLY at K978 acts as a novel risk in colorectal cancer chemoresistance. The deacetylation of K978 induces ACLY relocation to the nucleus and promotes its binding to RBM15, a m6A methylation modification “writer”.
Jun Wen, Mengqin Shen, Haitao Zhao, Liu Liu, Qian Hua, Xiaoping Zhao, Jianjun Liu, Haizhong Feng, Gang Huang   +8 more
wiley   +1 more source

DNA microarray analysis of Staphylococcus aureus from Nigeria and South Africa. [PDF]

PLoS One, 2021
Shittu AO, Adesoji T, Udo EE.
europepmc   +1 more source