Advanced Science, EarlyView.This study unveils ITGA2⁺ tumor cells as key drivers of pediatric thyroid cancer aggressiveness. These cells orchestrate dual oncogenic pathways: GLUT1‐mediated glycolytic reprogramming and M2 macrophage polarization. This metabolic‐immunological crosstalk promotes tumor progression and metastasis.
Zhi‐jun Zhan +11 more
wiley +1 more source
Diagnostic performance of DNA microarray for detecting rifampicin and isoniazid resistance in Mycobacterium tuberculosis. [PDF]
J Thorac Dis, 2021 Sun B, Sun Y.
europepmc +1 more source
Manufacturing DNA microarrays of high spot homogeneity and reduced background signal [PDF]
, 2001 Frank Diehl
openalex +1 more source
A Genome-Wide Analysis Reveals Significant Overlap of Transcription and DNA Repair in Stationary Phase Yeast [PDF]
, 2008 The association between transcription and DNA repair is acknowledged as a player in the generation of mutations in a non-random fashion in prokaryotes and eukaryotes.
Abraham Korol +5 more
core +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Advanced Science, EarlyView.Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
Short-term in vivo testing to discriminate genotoxic carcinogens from non-genotoxic carcinogens and non-carcinogens using next-generation RNA sequencing, DNA microarray, and qPCR. [PDF]
Genes Environ, 2023 Furihata C, Suzuki T.
europepmc +1 more source
Pathogen Response Genes Mediate Caenorhabditis elegans Innate Immunity
, 2012 Innate immunity is crucial in the response and defense against pathogens for invertebrates and vertebrates alike. The soil nematode Caenorhabditis elegans is a useful model to study the eukaryotic innate immune response to microbial pathogenesis.
Anthony, Hannah L.
core
Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond
Advanced Science, EarlyView.Dental stem cell (DSC) aging involves genomic instability, mitochondrial dysfunction, telomere attrition, and epigenetic alterations, leading to impaired proliferation, reduced differentiation potential, and pro‐inflammatory secretory activity. These processes drive cellular senescence and compromise regenerative and immunomodulatory functions, thereby
Xinyuan Zhao +7 more
wiley +1 more source
An Algorithm for the Selection of Probes for Specific Detection of Human Disease Pathogens Using the DNA Microarray Technology. [PDF]
Sovrem Tekhnologii Med, 2022 Filatova EN +4 more
europepmc +1 more source