Results 201 to 210 of about 413,268 (291)

Novel Evolutionarily Conserved Oncogene COA4 is Driven by KRAS Mutant and Promotes Cancer Metastasis Through Dual Mitochondrial Metabolism‐Dependent and ‐Independent Mechanisms

open access: yesAdvanced Science, EarlyView.
In KRAS‐mutant tumors, KRAS transcriptionally upregulates COA4 via the PI3K/AKT/E2F1 axis, promoting metastasis. Mechanistically, COA4 enhances tumor cell migration through dual pathways: within mitochondria, it boosts oxidative phosphorylation; in the cytoplasm, it binds and activates CDC42 to stimulate pseudopodia formation.
Xingzhao Ji   +14 more
wiley   +1 more source

Development of DNA Microarray for Parallel Detection of Community-Acquired Pneumonia Bacterial Pathogens. [PDF]

open access: yesSovrem Tekhnologii Med
Sakharnov NA   +4 more
europepmc   +1 more source

Genomic Profiling of the Response of Candida albicans to Itraconazole Treatment Using a DNA Microarray

open access: green, 2001
Marianne D. De Backer   +5 more
openalex   +1 more source

Long Non‐Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R‐AKT‐mTOR Axis and Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The limited understanding of IGFR pathway activation hinders its clinical application in HCC. Here, IGFRIL is identified as a novel non‐coding activator of the IGF1R, which recruits PTBP1 to destabilize IGFBP3 mRNA and activates IGF1R, and proposes IGFRIL as a novel actionable target for HCC patients.
Jing Zhang   +28 more
wiley   +1 more source

Fabrication of DNA Microarrays Using Unmodified Oligonucleotide Probes

open access: gold, 2001
Douglas R. Call   +2 more
openalex   +1 more source

DNA microarrays to study gene expression profiles in testis of fertile and infertile men. [PDF]

open access: bronze, 2001
Pasquale Patrizio   +4 more
openalex   +1 more source

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