Results 231 to 240 of about 2,563,210 (334)

A tiling resolution DNA microarray with complete coverage of the human genome

open access: yesNature Genetics, 2004
A. Ishkanian   +12 more
semanticscholar   +1 more source

Targeting HDAC and PARP Enhances STING‐Dependent Antitumor Immunity in STING‐Deficient Tumor

open access: yesAdvanced Science, EarlyView.
Dual HDAC and PARP inhibition restores STING signaling, enhances interferon response, and boosts antitumor immunity in STING‐deficient tumors. . Abstract The stimulator of interferon genes (STING)‐mediated innate immune pathway plays an important role in tumor immunosurveillance.
Chengzhou Mao   +10 more
wiley   +1 more source

SenExo‐cCCT2 Reprograms Senescence Response and Anti‐Tumor Immunity Following FOLFIRINOX Chemotherapy in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
This study demonstrates that SenExo‐cCCT2 enables targeted delivery of cCCT2 to pancreatic cancer cells, where it disrupts IPO13‐mediated nuclear translocation of UBC9, impairing SUMOylation‐dependent DNA damage repair and inducing senescence. Senescent tumor cells secrete CXCL10 to recruit CD8⁺ T‐cells while upregulating PD‐L1.
Shuncang Zhu   +18 more
wiley   +1 more source

Reliability and reproducibility issues in DNA microarray measurements.

open access: yesTrends in Genetics, 2006
S. Drăghici   +3 more
semanticscholar   +1 more source

Experimental Design of DNA Microarray Experiments

open access: yesBioTechniques, 2003
Richard M. Simon, Kevin Dobbin
doaj   +1 more source

Cancer pathway analysis, DNA microarrays, and the identification of therapeutic targets [PDF]

open access: bronze, 2001
Filippo Randazzo   +19 more
openalex   +1 more source

SNORA58 Facilitates Radioresistance via Suppressing JNK1‐Mediated Ferroptosis in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
In ESCC patients, SNORA58 exhibits heterogeneous expression patterns. Its aberrant overexpression stabilizes CTCF by inhibiting ubiquitin‐mediated degradation, leading to the attenuation of JNK1‐mediated ferroptosis induced by radiotherapy through disruption of intracellular iron homeostasis, and ultimately contributes to radioresistance ...
Yinli Zheng   +14 more
wiley   +1 more source

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