Results 271 to 280 of about 2,576,927 (378)

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li   +12 more
wiley   +1 more source

Antisense DNAs as multisite genomic modulators identified by DNA microarray

open access: green, 2001
Yee Sook Cho   +5 more
openalex   +1 more source

Single‐Cell Nucleus Extraction with Cellular Indexing

open access: yesAdvanced Science, EarlyView.
VacTrap is a multilayer, high‐throughput microfluidic system that isolates and spatially indexes single nuclei from hundreds of cells within minutes. Using dissolvable hydrogel trapdoors triggered by chemical and vacuum actuation, VacTrap synchronously transfers nuclei while preserving spatial links to parent cells.
Trinh Lam   +7 more
wiley   +1 more source

Application of L-cystein derivative to DNA microarray [PDF]

open access: bronze, 2002
Gen Nakauchi   +4 more
openalex   +1 more source

Rapid Detection of Respiratory Tract Viral Infections and Coinfections in Patients with Influenza-Like Illnesses by Use of Reverse Transcription-PCR DNA Microarray Systems

open access: yesJournal of Clinical Microbiology, 2010
F. Renois   +7 more
semanticscholar   +1 more source

Identifying Key Questions and Challenges in Microchimerism Biology

open access: yesAdvanced Science, EarlyView.
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua   +31 more
wiley   +1 more source

Clinical Significance of Copper Chaperone for Superoxide Dismutase in Colorectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Targeting Cu transport proteins is an innovative therapeutic approach for combating cancer. However, the mechanisms underlying the malignant potential of Cu transport proteins remain largely unknown. To address this issue, we focused on the oncogenic potential of copper chaperones for superoxide dismutase (CCS) in colorectal cancer (
Nobuo Takiguchi   +15 more
wiley   +1 more source

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